HPS6 and OSGEP

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HPS6	OSGEP
Gene Name		Hermansky-Pudlak syndrome 6	O-sialoglycoprotein endopeptidase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane BLOC-2 Complex Early Endosome Membrane	EKC/KEOPS Complex Nucleus Cytoplasm
	Molecular Function	Rab GTPase Binding GTP-dependent Protein Binding	Transferase Activity, Transferring Acyl Groups Other Than Amino-acyl Groups Metal Ion Binding
	Biological Process	Organelle Organization Blood Coagulation Melanocyte Differentiation Protein Localization To Membrane	Threonylcarbamoyladenosine Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CREB1 EP300 HPS5 KIAA0020 MARK4 MNAT1 OSGEP PIK3CB TTC19	23 interactors: C19orf60 CIAPIN1 CRIP2 EMCN GP1BA HPS6 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 SF3B3 SHC1 SP110 SPRED1 TNS1 WDR82 WIZ ZNF579 ZNF775
Entrez ID		79803	55644
HPRD ID		08471	10133
Ensembl ID		ENSG00000166189	ENSG00000092094
Uniprot IDs		Q86YV9	Q9NPF4
PDB IDs
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Viral Transcription Regulation Of Viral Transcription Positive Regulation Of Viral Process Cell Cycle Process Histone H2B Acetylation Protein Stabilization Posttranscriptional Regulation Of Gene Expression Threonylcarbamoyladenosine Biosynthetic Process Viral Process Cell Cycle Regulation Of Body Fluid Levels Phosphatidylinositol-mediated Signaling N-terminal Peptidyl-lysine Acetylation Regulation Of Protein Stability Notch Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Viral Process G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Mitotic Cell Cycle Process Circadian Rhythm Threonylcarbamoyladenosine Metabolic Process Regulation Of Tubulin Deacetylation Cellular Response To Fibroblast Growth Factor Stimulus Mitotic Cell Cycle Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Organelle Organization Phosphorylation Negative Regulation Of Transcription By Competitive Promoter Binding Lung Development Positive Regulation By Host Of Viral Transcription Embryonic Cleavage Mitochondrial Respiratory Chain Complex III Assembly Respiratory Tube Development Regulation Of Cellular Protein Metabolic Process Response To Hormone Fc Receptor Signaling Pathway N-terminal Protein Amino Acid Acetylation Response To Stress Regulation Of Clathrin-mediated Endocytosis Lung Saccule Development	Regulation Of Cellular Ketone Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Process
Tagcloud ?			ancient antigen associate bc biochemically box characterizing cul2 cullin2 deeper e3 ekc interactome keops lage3 ligase link melanoma mined oncogenesis oncoprotein orthologues overexpressed prame preferentially recruits reveal ubiquitin understood
Tagcloud (Difference) ?			ancient antigen associate bc biochemically box characterizing cul2 cullin2 deeper e3 ekc interactome keops lage3 ligase link melanoma mined oncogenesis oncoprotein orthologues overexpressed prame preferentially recruits reveal ubiquitin understood
Tagcloud (Intersection) ?