HPS6 and OSGEP

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		HPS6	OSGEP
Description		HPS6 biogenesis of lysosomal organelles complex 2 subunit 3	O-sialoglycoprotein endopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Endosome Early Endosome Endoplasmic Reticulum Cytosol Membrane BLOC-2 Complex Early Endosome Membrane	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding GTP-dependent Protein Binding Small GTPase Binding	Protein Binding Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Metal Ion Binding TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity
	Biological Process	Lipid Metabolic Process Blood Coagulation Protein Secretion Lysosome Localization Pigmentation Lipid Homeostasis Platelet Dense Granule Organization Protein Localization To Membrane Melanosome Assembly	TRNA Threonylcarbamoyladenosine Modification TRNA Modification TRNA Processing
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)	Food addiction ( 27106561)
Interacting Genes		11 interacting genes: CREB1 EP300 HPS5 MARK4 MNAT1 OSGEP PIK3CB PUM3 SUMO2 TTC19 UBC	25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 LGALS4 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 WDR82 WIZ ZNF579 ZNF775
Entrez ID		79803	55644
HPRD ID		08471	10133
Ensembl ID		ENSG00000166189	ENSG00000092094
Uniprot IDs		Q86YV9	Q9NPF4
PDB IDs			6GWJ
Enriched GO Terms of Interacting Partners?		Protein Tag Activity Nucleoplasm Chemotaxis To Arachidonate Transcription Coactivator Binding Tau Protein Binding Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Midbody Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta3 Production Secretory Granule Organization Locomotion Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity BLOC-2 Complex TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity
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