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C8orf74 and SUV39H2
Number of citations of the paper that reports this interaction (PMID
23455924
)
3
Data Source:
BioGRID
(two hybrid)
C8orf74
SUV39H2
Gene Name
chromosome 8 open reading frame 74
suppressor of variegation 3-9 homolog 2 (Drosophila)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Chromatin
Nucleoplasm
Nuclear Heterochromatin
Molecular Function
Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
Histone Methyltransferase Activity (H3-K9 Specific)
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Chromatin Assembly Or Disassembly
Chromatin Remodeling
Transcription, DNA-templated
Male Meiosis
Cell Differentiation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Pathways
Chromatin modifying enzymes
Chromatin organization
PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
KDM1A
PRMT6
SUV39H1
SUV39H2
39 interactors:
AKAP9
APPL2
BLZF1
C8orf74
CBX5
CBX7
CCDC151
CCDC37
CDCA4
CEP70
CGGBP1
EWSR1
FAM20C
GSTCD
ID2
KCTD17
KLF3
KLHDC4
LCA5L
LNX1
LRIF1
MCM3AP
MRFAP1
MTF2
MYL12A
NME4
PHF19
PNMA1
POLR3F
RAB3IP
RASSF1
SHC1
SMAD5
SNF8
UBE2V2
WIZ
ZNF212
ZNF557
ZNF57
Entrez ID
203076
79723
HPRD ID
19096
07580
Ensembl ID
ENSG00000171060
ENSG00000152455
Uniprot IDs
Q6P047
Q9H5I1
PDB IDs
2R3A
Enriched GO Terms of Interacting Partners
?
Histone Modification
Histone H3-K9 Dimethylation
Chromatin Modification
Histone Methylation
Histone H3-K9 Trimethylation
Chromatin Organization
Peptidyl-lysine Dimethylation
Protein Methylation
Negative Regulation Of Circadian Rhythm
Chromosome Organization
Histone H3-K9 Methylation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Peptidyl-lysine Trimethylation
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Histone H3-K9 Modification
Methylation
Negative Regulation Of Cellular Metabolic Process
Histone Lysine Methylation
Transcription, DNA-templated
Regulation Of Circadian Rhythm
Peptidyl-lysine Methylation
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
RNA Biosynthetic Process
Cellular Response To Oxygen Levels
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Primitive Erythrocyte Differentiation
Peptidyl-amino Acid Modification
Histone H3-R2 Methylation
Organelle Organization
RNA Metabolic Process
Cellular Protein Modification Process
Response To Stress
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Peptidyl-lysine Modification
Response To Hypoxia
Rhythmic Process
Cellular Response To Stress
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Protein Metabolic Process
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Histone H3-K4 Demethylation
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Positive Regulation Of Histone H3-K27 Methylation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Histone H3-K27 Methylation
Regulation Of RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Osteoblast Differentiation
Biosynthetic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Golgi To Plasma Membrane Transport
Positive Regulation Of Histone Methylation
Nitrogen Compound Metabolic Process
Positive Regulation Of DNA Metabolic Process
Osteoclast Maturation
Regulation Of Histone Methylation
Regulation Of Ossification
Protein Targeting
Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of RNA Biosynthetic Process
Establishment Of Protein Localization To Membrane
Positive Regulation Of DNA Replication
Positive Regulation Of Histone Modification
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Positive Regulation Of Osteoblast Differentiation
Myeloid Cell Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Establishment Of Protein Localization To Plasma Membrane
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Tagcloud
?
a7
circular
dichroism
dim
g12
g13
g9a
h3k9
h3k9me0
h3k9me1
h3k9me2
h3k9me3
introduce
introduces
k14
labrador
n324k
pkmts
prefers
processive
r8
readout
recognizes
renders
retrievers
s10
t11
t6
Tagcloud (Difference)
?
a7
circular
dichroism
dim
g12
g13
g9a
h3k9
h3k9me0
h3k9me1
h3k9me2
h3k9me3
introduce
introduces
k14
labrador
n324k
pkmts
prefers
processive
r8
readout
recognizes
renders
retrievers
s10
t11
t6
Tagcloud (Intersection)
?