ANKRD55 and FHL5

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 50
  • Data Source:
  • BioGRID (two hybrid)

ANKRD55

FHL5
Description ankyrin repeat domain 55 four and a half LIM domains 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Celiac disease or Rheumatoid arthritis ( 21383967)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • IgA levels ( 28628107)
  • IgG glycosylation ( 23382691)
  • Immature fraction of reticulocytes ( 32888494)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Lung function (FEV1) ( 30061609)
  • Macular thickness ( 30535121)
  • Monocyte count ( 32888494 27863252)
  • Monocyte percentage of white cells ( 32888494)
  • Multiple sclerosis ( 24076602 27386562 31604244)
  • Optic disc size ( 31809533)
  • Pediatric autoimmune diseases ( 26301688)
  • Post-traumatic stress disorder ( 27167565)
  • Reticulocyte fraction of red cells ( 32888494)
  • Rheumatoid arthritis ( 24390342 23143596 30572963 30423114)
  • Rheumatoid arthritis (ACPA-negative) ( 23143596)
  • Rheumatoid arthritis (ACPA-positive) ( 24532676 23143596)
  • Sero-negative rheumatoid arthritis ( 28706201)
  • Serum alkaline phosphatase levels ( 33547301)
  • Triglycerides ( 20686565)
  • Type 1 diabetes ( 34127860)
  • Type 2 diabetes ( 29358691 22885922 26818947 26961502 27189021 32499647 30718926 30297969 28869590)
  • Urate levels ( 23263486)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)
Interacting Genes 22 interacting genes: ABI2 ANKS1A BACH2 BANP BOLA2 BOLA2B CABP5 CFAP206 CLIC3 FHL2 FHL5 FRS3 HGS HSF2BP NCK2 NOXA1 PFDN5 PTK6 TEKT4 TRIM23 ZMYND19 ZSCAN1 89 interacting genes: ABI2 ADAM12 ADAMTSL5 AGXT ANKRD55 ANKS1A ATOSB BANP BBC3 BCL6B CATSPER1 CDC20B CFP CNNM3 COIL CREB1 CREM CRYBA2 CRYBA4 CTSZ DCDC2B DLGAP4 DMRT3 DNAL4 DTX2 FARS2 FEZF1 FHL2 GARIN6 GPS2 GSTP1 HAPLN2 HCK HDX HEY2 HOXA1 HOXB9 IL16 IP6K3 KIF17 KIR2DL4 LMO2 LRRC41 MAGOHB MISP MYOZ3 NEK6 NPDC1 NUFIP2 OTX1 PIN1 PLEKHA2 PLEKHN1 PPP1R18 QRICH1 RAB26 RAB3IL1 RPS21 SAXO1 SAXO4 SCNM1 SDCBP SEC31A SHFL SLIT1 SMAD1 SPRY1 SRF TUSC2 TXN2 YPEL3 ZBTB16 ZNF124 ZNF23 ZNF250 ZNF251 ZNF408 ZNF417 ZNF440 ZNF446 ZNF564 ZNF581 ZNF587 ZNF613 ZNF688 ZNF764 ZNF766 ZNF792 ZNHIT1
Entrez ID 79722 9457
HPRD ID 07758 05497
Ensembl ID ENSG00000164512 ENSG00000112214
Uniprot IDs Q3KP44 Q5TD97
PDB IDs 1X68
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?