FHL5 and KIF17

Number of citations of the paper that reports this interaction (PubMedID 12493914)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		FHL5	KIF17
Description		four and a half LIM domains 5	kinesin family member 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Z Disc	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Microtubule Organizing Center Cytosol Cytoskeleton Kinesin Complex Microtubule Cilium Axoneme Microtubule Cytoskeleton Dendrite Photoreceptor Connecting Cilium Dendrite Cytoplasm Ciliary Basal Body Cell Projection Neuron Projection Postsynapse Periciliary Membrane Compartment
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Microtubule-based Process Microtubule-based Movement Protein Transport Vesicle-mediated Transport Cell Projection Organization Protein-containing Complex Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex
Pathways			Intraflagellar transport Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Cerebral blood flow ( 28627999) Cluster headache ( 34184781) Coronary artery disease ( 29212778) Coronary heart disease ( 22319020) Headache ( 29397368) Metabolite levels ( 23823483) Migraine ( 27322543 27182965 23793025 22683712) Migraine - clinic-based ( 23793025) Migraine without aura ( 27322543 23793025) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) Pulse pressure ( 30578418) Spatial memory ( 31596458)	Ceramide levels (C24:0) ( 32489964) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes		89 interacting genes: ABI2 ADAM12 ADAMTSL5 AGXT ANKRD55 ANKS1A ATOSB BANP BBC3 BCL6B CATSPER1 CDC20B CFP CNNM3 COIL CREB1 CREM CRYBA2 CRYBA4 CTSZ DCDC2B DLGAP4 DMRT3 DNAL4 DTX2 FARS2 FEZF1 FHL2 GARIN6 GPS2 GSTP1 HAPLN2 HCK HDX HEY2 HOXA1 HOXB9 IL16 IP6K3 KIF17 KIR2DL4 LMO2 LRRC41 MAGOHB MISP MYOZ3 NEK6 NPDC1 NUFIP2 OTX1 PIN1 PLEKHA2 PLEKHN1 PPP1R18 QRICH1 RAB26 RAB3IL1 RPS21 SAXO1 SAXO4 SCNM1 SDCBP SEC31A SHFL SLIT1 SMAD1 SPRY1 SRF TUSC2 TXN2 YPEL3 ZBTB16 ZNF124 ZNF23 ZNF250 ZNF251 ZNF408 ZNF417 ZNF440 ZNF446 ZNF564 ZNF581 ZNF587 ZNF613 ZNF688 ZNF764 ZNF766 ZNF792 ZNHIT1	8 interacting genes: APBA1 FHL5 FXR1 GFI1B MAP3K10 MAP3K11 PHAF1 XPO1
Entrez ID		9457	57576
HPRD ID		05497	10388
Ensembl ID		ENSG00000112214	ENSG00000117245
Uniprot IDs		Q5TD97	A0A0A0MRS8 Q9P2E2
PDB IDs		1X68
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Nucleus Heart Trabecula Formation Regulation Of Primary Metabolic Process Identical Protein Binding Regulation Of Macromolecule Metabolic Process Zinc Ion Binding ATF4-CREB1 Transcription Factor Complex Regulation Of Metabolic Process Tangential Migration From The Subventricular Zone To The Olfactory Bulb	JUN Kinase Kinase Kinase Activity Positive Regulation Of JUN Kinase Activity MAP Kinase Kinase Kinase Activity Positive Regulation Of MAP Kinase Activity Presynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Protein Serine/threonine Kinase Activity JNK Cascade Regulation Of MAP Kinase Activity Cellular Localization Dendritic Spine Regulation Of Macromolecule Metabolic Process Gamma-aminobutyric Acid Secretion Positive Regulation Of Kinase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Kinase Activity Negative Regulation Of RNA Metabolic Process Protein Autophosphorylation Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of JNK Cascade Protein Homodimerization Activity Regulation Of JNK Cascade Regulation Of Protein Metabolic Process Annulate Lamellae Cellular Response To Salt Ribosomal Small Subunit Export From Nucleus Response To Triglyceride Ribosomal Large Subunit Export From Nucleus MRNA Transport Cellular Response To Triglyceride RNA Transport RNA Strand Annealing Activity Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Intracellular Membraneless Organelle Regulation Of Metabolic Process Nucleobase-containing Compound Transport Nuclear Envelope Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Phosphorylation MAPK Cascade Mitogen-activated Protein Kinase Kinase Binding Nuclear Export Signal Receptor Activity Ribosomal Subunit Export From Nucleus Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Nuclear Pore Complex Assembly Positive Regulation Of Phosphorylation Regulation Of Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?