FHL5 and RAB26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FHL5	RAB26
Description		four and a half LIM domains 5	RAB26, member RAS oncogene family
Image
GO Annotations	Cellular Component	Nucleus Z Disc	Golgi Membrane Endosome Golgi Apparatus Plasma Membrane Membrane Transport Vesicle Membrane Secretory Granule Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GMP Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Protein Transport Regulation Of Exocytosis Exocrine System Development Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Regulation Protein Catabolic Process At Presynapse
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Cerebral blood flow ( 28627999) Cluster headache ( 34184781) Coronary artery disease ( 29212778) Coronary heart disease ( 22319020) Headache ( 29397368) Metabolite levels ( 23823483) Migraine ( 27322543 27182965 23793025 22683712) Migraine - clinic-based ( 23793025) Migraine without aura ( 27322543 23793025) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) Pulse pressure ( 30578418) Spatial memory ( 31596458)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		89 interacting genes: ABI2 ADAM12 ADAMTSL5 AGXT ANKRD55 ANKS1A ATOSB BANP BBC3 BCL6B CATSPER1 CDC20B CFP CNNM3 COIL CREB1 CREM CRYBA2 CRYBA4 CTSZ DCDC2B DLGAP4 DMRT3 DNAL4 DTX2 FARS2 FEZF1 FHL2 GARIN6 GPS2 GSTP1 HAPLN2 HCK HDX HEY2 HOXA1 HOXB9 IL16 IP6K3 KIF17 KIR2DL4 LMO2 LRRC41 MAGOHB MISP MYOZ3 NEK6 NPDC1 NUFIP2 OTX1 PIN1 PLEKHA2 PLEKHN1 PPP1R18 QRICH1 RAB26 RAB3IL1 RPS21 SAXO1 SAXO4 SCNM1 SDCBP SEC31A SHFL SLIT1 SMAD1 SPRY1 SRF TUSC2 TXN2 YPEL3 ZBTB16 ZNF124 ZNF23 ZNF250 ZNF251 ZNF408 ZNF417 ZNF440 ZNF446 ZNF564 ZNF581 ZNF587 ZNF613 ZNF688 ZNF764 ZNF766 ZNF792 ZNHIT1	8 interacting genes: APP FHL5 GCH1 KRT33B OIP5 RIMS1 SNCA UNKL
Entrez ID		9457	25837
HPRD ID		05497	05676
Ensembl ID		ENSG00000112214	ENSG00000167964
Uniprot IDs		Q5TD97	Q9ULW5
PDB IDs		1X68	2G6B
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Nucleus Heart Trabecula Formation Regulation Of Primary Metabolic Process Identical Protein Binding Regulation Of Macromolecule Metabolic Process Zinc Ion Binding ATF4-CREB1 Transcription Factor Complex Regulation Of Metabolic Process Tangential Migration From The Subventricular Zone To The Olfactory Bulb	Regulation Of Presynapse Organization Response To Copper Ion Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Presynapse Assembly Amyloid Fibril Formation Regulation Of Superoxide Metabolic Process Regulation Of Neurotransmitter Uptake Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Cellular Response To Copper Ion Catecholamine Biosynthetic Process Biogenic Amine Biosynthetic Process Dopamine Biosynthetic Process Dopamine Metabolic Process Synaptic Vesicle Priming Synaptic Vesicle Exocytosis Metal Ion Binding Amine Biosynthetic Process Synapse Organization Catecholamine Metabolic Process Modulation Of Excitatory Postsynaptic Potential Amyloid-beta Complex Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Macrophage Activation Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Biogenic Amine Metabolic Process GTP Cyclohydrolase I Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Amine Metabolic Process Adult Locomotory Behavior Response To Interleukin-1 Phenol-containing Compound Metabolic Process Regulation Of Neurotransmitter Secretion Zinc Ion Binding Acetylcholine Receptor Activator Activity Regulation Of Membrane Potential Protein Tetramerization Lipoprotein Particle Positive Regulation Of Protein Import Response To Type II Interferon
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?