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SH3YL1
Description
SH3 and SYLF domain containing 1
Image
GO Annotations
Cellular Component
Ruffle Membrane
Molecular Function
Protein Binding
Phosphatase Binding
Phosphatidylinositol Binding
Biological Process
Phosphatidylinositol Biosynthetic Process
Regulation Of Ruffle Assembly
Pathways
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Apolipoprotein A1 levels (
32203549
)
Blood urea nitrogen levels (
31152163
)
Body mass index (
26426971
)
Body mass index (age>50) (
26426971
)
Body mass index x age interaction (
26426971
)
Body mass index x sex x age interaction (4df test) (
26426971
)
Estimated glomerular filtration rate (
31152163
)
HDL cholesterol (
30275531
)
HDL cholesterol levels (
32203549
)
Large artery stroke (
28265093
)
Mitochondrial DNA levels (
25240745
)
Night sleep phenotypes (
27126917
)
Refractive error (
32231278
)
Waist circumference adjusted for body mass index (
34021172
)
Interacting Genes
11 interacting genes:
AR
ERRFI1
GFAP
HELZ
KHDRBS1
PRB3
SH3D19
SYNJ1
VIM
VPS37B
ZBTB7B
Entrez ID
26751
HPRD ID
15336
Ensembl ID
ENSG00000035115
Uniprot IDs
Q96HL8
PDB IDs
2D8H
Enriched GO Terms of Interacting Partners
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Bergmann Glial Cell Differentiation
Astrocyte Development
Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis
Prostate Induction
Gene Expression
Cellular Response To Steroid Hormone Stimulus
Nuclear Receptor-mediated Signaling Pathway
Tertiary Branching Involved In Mammary Gland Duct Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Male Somatic Sex Determination
Positive Regulation Of Integrin Biosynthetic Process
Positive Regulation Of Schwann Cell Proliferation
Astrocyte Differentiation
Kinase Binding
Intermediate Filament Organization
Schwann Cell Proliferation
Glial Cell Development
Structural Constituent Of Cytoskeleton
Intermediate Filament Cytoskeleton
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Regulation Of Collagen Metabolic Process
Regulation Of Collagen Biosynthetic Process
Phosphatidylinositol Phosphate 5-phosphatase Activity
Phosphatidylinositol-4-phosphate Phosphatase Activity
Synaptic Vesicle Uncoating
Positive Regulation Of Endosome Organization
Grb2-Sos Complex
Negative Regulation Of NK T Cell Activation
Negative Regulation Of NK T Cell Proliferation
Positive Regulation Of SREBP Signaling Pathway
Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Uterine Epithelium Development
Response To 1-oleoyl-sn-glycerol 3-phosphate
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Male Genitalia Morphogenesis
POU Domain Binding
Glial Cell Differentiation
Phosphatidylinositol Phosphate 4-phosphatase Activity
SH3 Domain Binding
NK T Cell Differentiation
Negative Regulation Of Protein Autophosphorylation
Oviduct Epithelium Development
Cellular Response To Lipid
Negative Regulation Of Neuron Projection Development
Tagcloud
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