SH3YL1 and ZBTB7B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SH3YL1	ZBTB7B
Gene Name		SH3 and SYLF domain containing 1	zinc finger and BTB domain containing 7B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Membrane	Nucleus Nucleoplasm
	Molecular Function	Phosphatase Binding Phosphatidylinositol Binding	DNA Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Ruffle Assembly	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Ectoderm Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		7 interactors: GFAP HELZ KHDRBS1 SH3D19 VIM VPS37B ZBTB7B	17 interactors: BCL6 EP300 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN PIN1 RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 ZBTB5 ZNF277
Entrez ID		26751	51043
HPRD ID		15336	09625
Ensembl ID		ENSG00000035115	ENSG00000160685
Uniprot IDs		Q96HL8	O15156
PDB IDs		2D8H
Enriched GO Terms of Interacting Partners?		Bergmann Glial Cell Differentiation Intermediate Filament Organization Astrocyte Development Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Positive Regulation Of Schwann Cell Proliferation Glial Cell Development Negative Regulation Of Neuron Projection Development Positive Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Projection Organization Glial Cell Differentiation Negative Regulation Of Neuron Differentiation Gliogenesis Negative Regulation Of Neurogenesis Viral Protein Processing Cytoskeleton Organization Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Development Positive Regulation Of Glial Cell Proliferation Regulation Of Neurotransmitter Uptake Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Translational Initiation Regulation Of Neuron Projection Development Lens Fiber Cell Development Virion Assembly Ectoderm Development Regulation Of Cell Projection Organization Intracellular Transport Of Virus	Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Signaling Regulation Of Cell-cell Adhesion Regulation Of Cellular Senescence Regulation Of Lymphocyte Activation Positive Regulation Of Organelle Organization Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cellular Component Organization ERBB Signaling Pathway Regulation Of Cell Activation Regulation Of Signal Transduction Regulation Of Organelle Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Ras Protein Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Process Negative Regulation Of ERBB Signaling Pathway Regulation Of Protein Deacetylation Positive Regulation Of Cell-cell Adhesion Cell Surface Receptor Signaling Pathway RNA Biosynthetic Process Histone H2B Acetylation RNA Metabolic Process Regulation Of Cell Adhesion Regulation Of DNA Recombination Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Cellular Component Biogenesis T Cell Costimulation Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Cellular Response To Stimulus Immune Response Regulation Of Immune System Process Establishment Of Protein Localization To Organelle Nucleobase-containing Compound Metabolic Process Defense Response Regulation Of Actin Cytoskeleton Organization Innate Immune Response Positive Regulation Of Cell Adhesion Negative Regulation Of Mast Cell Cytokine Production N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Isotype Switching To IgE Isotypes Cell Migration
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