ZC2HC1C and BICD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZC2HC1C	BICD2
Description		zinc finger C2HC-type containing 1C	BICD cargo adaptor 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Cytoskeletal Anchor Activity Small GTPase Binding Dynactin Binding Dynein Light Intermediate Chain Binding Dynein Complex Binding
	Biological Process		Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Protein Transport Protein Localization To Golgi Apparatus MRNA Transport Centrosome Localization Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center
Pathways			COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Refractive error ( 32231278)	Appendicular lean mass ( 33097823) Haemorrhoidal disease ( 33888516) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Malaria ( 31844061) Neutrophil count ( 32888494) Platelet count ( 32888494) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494)
Interacting Genes		80 interacting genes: ACTMAP ACTN2 ANKS1A ARMC7 BANP BICD2 BYSL CABP5 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC85B CCDC88B CIB3 CLIC3 CRACR2A DDX6 EMILIN1 ENKD1 FAM90A1 FBXO7 FGFR1OP2 FSD2 GFAP GOLGA1 GOLGA2 GOLGA6A GPRASP2 HOOK2 HSF2BP KASH5 KAT5 KATNBL1 KIF9 KRT15 KRT20 KRT40 LMNA LMNB2 LZTS2 MAPK9 MAPRE3 MID2 MTUS2 NCKIPSD NDEL1 NDOR1 NEK6 NOXA1 NTAQ1 OSGIN1 PFDN5 PIBF1 PNMA1 POLR1C PRKAB2 PSTPIP1 RABGEF1 RAD51D RINT1 SFN SIKE1 SMARCD1 SORBS3 SPAG5 TFIP11 TNPO2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM55 TRIM63 UBASH3A VPS52 ZNF655 ZNF76	51 interacting genes: ARHGAP45 CBR3 CCDC187 CCHCR1 DCTN1 DCTN2 DCX DSCR9 FAM110A FAM161A FAM161B FAM50B GSK3B HDAC4 LNX1 MFAP1 MOS NEK9 NXF1 PCM1 PMF1 POLDIP3 PPP1R18 PRC1 PRPF18 PRPF31 PRPF6 RAB6A RAB6B RBM22 RBM41 SNW1 TBRG4 TCEA2 TCEANC TFIP11 TSGA10IP USP2 UTP14A UTP14C YES1 YTHDF1 ZC2HC1C ZMAT2 ZNF417 ZNF624 ZNF648 ZNF669 ZNF670 ZSCAN12 ZSCAN23
Entrez ID		79696	23299
HPRD ID		16607	09826
Ensembl ID		ENSG00000119703	ENSG00000185963
Uniprot IDs		J3KMY6 Q53FD0	Q8TD16 Q96FU2
PDB IDs			6OFP 6PSE
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cytoskeleton Cytoplasm Microtubule Cytoskeleton Organization Protein Binding Microtubule Microtubule-based Process Microtubule Binding Organelle Organization Identical Protein Binding Microtubule Organizing Center Intracellular Transport Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Centrosome Spindle Localization Establishment Of Localization In Cell Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Cellular Component Organization Establishment Of Organelle Localization Membraneless Organelle Assembly Cellular Localization Organelle Localization Establishment Of Spindle Orientation Intermediate Filament Cytoskeleton Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Spindle Assembly Protein Localization To Cytoskeleton Supramolecular Fiber Organization Spindle Pole Spindle Organization Intracellular Protein Localization Establishment Of Spindle Localization Positive Regulation Of Autophagy Nuclear Pore Localization Dynein Light Intermediate Chain Binding Regulation Of Autophagy Microtubule Nucleation Intermediate Filament Organization Chromosome Localization Establishment Of Mitotic Spindle Orientation Mitotic Spindle Pole Thioesterase Binding Establishment Of Mitotic Spindle Localization Regulation Of Organelle Organization Golgi Cis Cisterna	Centrosome Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Processing U4/U6 X U5 Tri-snRNP Complex RNA Metabolic Process MRNA Metabolic Process U2-type Precatalytic Spliceosome Ciliary Basal Body Nuclear Speck Microtubule Cytoskeleton Organization Microtubule Anchoring Protein Localization To Golgi Membrane Catalytic Step 2 Spliceosome Spindle Microtubule Nucleoplasm Protein Binding Microtubule Anchoring At Centrosome Nucleus Microtubule-based Process Nucleic Acid Metabolic Process Microtubule Anchoring At Microtubule Organizing Center Microtubule Binding Cellular Response To Retinoic Acid Myosin V Binding Establishment Of Organelle Localization Zinc Ion Binding Spindle Pole Spliceosomal Tri-snRNP Complex Assembly Centriole Nucleic Acid Binding Positive Regulation Of Protein Export From Nucleus U5 SnRNP
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