ZC2HC1C and TRIM23

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ZC2HC1C	TRIM23
Description		zinc finger C2HC-type containing 1C	tripartite motif containing 23
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Nucleus Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Transferase Activity GDP Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Immune System Process Intracellular Protein Transport Positive Regulation Of Autophagy Vesicle-mediated Transport Protein Ubiquitination Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Refractive error ( 32231278)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		80 interacting genes: ACTMAP ACTN2 ANKS1A ARMC7 BANP BICD2 BYSL CABP5 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC85B CCDC88B CIB3 CLIC3 CRACR2A DDX6 EMILIN1 ENKD1 FAM90A1 FBXO7 FGFR1OP2 FSD2 GFAP GOLGA1 GOLGA2 GOLGA6A GPRASP2 HOOK2 HSF2BP KASH5 KAT5 KATNBL1 KIF9 KRT15 KRT20 KRT40 LMNA LMNB2 LZTS2 MAPK9 MAPRE3 MID2 MTUS2 NCKIPSD NDEL1 NDOR1 NEK6 NOXA1 NTAQ1 OSGIN1 PFDN5 PIBF1 PNMA1 POLR1C PRKAB2 PSTPIP1 RABGEF1 RAD51D RINT1 SFN SIKE1 SMARCD1 SORBS3 SPAG5 TFIP11 TNPO2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM55 TRIM63 UBASH3A VPS52 ZNF655 ZNF76	219 interacting genes: ACTN4 AKTIP ANKRD36BP1 ANKRD55 ANO1 AP3M1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 BAZ2B BICRAL BRME1 C8orf33 CARD9 CATSPERT CBX8 CCDC13 CCDC146 CCDC25 CCDC33 CDC20B CDC73 CDR2 CFAP53 CHP1P2 CIMIP4 COX5B CPNE7 CREB5 CSRP2 CWF19L2 CXCL14 CYTH1 CYTH2 DCX DEPP1 DMC1 DMRT3 DNAAF4 DOCK2 EAF2 EHHADH EIF3D ENKD1 EPN2 EXOC3-AS1 FAM110A FAM133A FAM193B FAM83A FAM90A1 FBF1 FHIT FLAD1 FXR2 GAD1 GATA2 GCC2-AS1 GEM GGA2 GGA3 GLIDR GMCL2 GPANK1 GPKOW HAPLN2 HAUS1 HGS HNRNPLL HOXB5 HSPB7 IL16 IQCE IQUB JOSD1 JRK KAT5 KIFC3 KLHL42 KRT6A KRT75 KRT76 LAGE3 LENG1 LGALS14 LGALS3 LGALS8 LINC00526 LINC01018 LMO2 LMO3 LNX1 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MSRB3 MTFR2 MYEF2 MYOM1 MYOZ1 NAB2 NEDD9 NEK6 NFU1 NOXA1 NTAQ1 NUDT21 NXT2 PDE4D PHF1 PIAS2 PIK3R2 PITX1 PKP4 PLEKHA2 POLI POLL POM121 PPIL2 PPP1R15B PPP1R18 PRPF18 PRPF31 PSMA1 PSMB1 RAD18 RAMAC RCAN3 RIBC1 RIBC2 RIN1 RNF126 RNF213 RNF32 RNF34 RNF6 RSRC2 RTP5 RUFY1 SCNM1 SF1 SH2D4A SIAH1 SIRPA SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SNRPB2 SNW1 SORBS3 SPG21 SUMO1P1 TACO1 TASOR2 TBC1D22B TCEA2 TCEANC TEPSIN TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TRIM55 TRIM63 TROAP TSEN54 TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U UBE2W UBOX5 UBQLN1 USP2 USP20 USP21 UTP23 VGLL1 WDR25 WHR1 ZBTB16 ZBTB4 ZC2HC1C ZFAND2A ZNF20 ZNF250 ZNF408 ZNF417 ZNF474 ZNF564 ZNF581 ZNF587 ZNF688 ZNF835
Entrez ID		79696	373
HPRD ID		16607	03449
Ensembl ID		ENSG00000119703	ENSG00000113595
Uniprot IDs		J3KMY6 Q53FD0	P36406
PDB IDs			5VZV 5VZW
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cytoskeleton Cytoplasm Microtubule Cytoskeleton Organization Protein Binding Microtubule Microtubule-based Process Microtubule Binding Organelle Organization Identical Protein Binding Microtubule Organizing Center Intracellular Transport Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Centrosome Spindle Localization Establishment Of Localization In Cell Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Cellular Component Organization Establishment Of Organelle Localization Membraneless Organelle Assembly Cellular Localization Organelle Localization Establishment Of Spindle Orientation Intermediate Filament Cytoskeleton Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Spindle Assembly Protein Localization To Cytoskeleton Supramolecular Fiber Organization Spindle Pole Spindle Organization Intracellular Protein Localization Establishment Of Spindle Localization Positive Regulation Of Autophagy Nuclear Pore Localization Dynein Light Intermediate Chain Binding Regulation Of Autophagy Microtubule Nucleation Intermediate Filament Organization Chromosome Localization Establishment Of Mitotic Spindle Orientation Mitotic Spindle Pole Thioesterase Binding Establishment Of Mitotic Spindle Localization Regulation Of Organelle Organization Golgi Cis Cisterna	Protein Binding Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Ubiquitination Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Nucleus Ubiquitin Protein Ligase Activity Proteolysis Involved In Protein Catabolic Process Protein K63-linked Ubiquitination Zinc Ion Binding Protein Modification Process Ubiquitin-protein Transferase Activator Activity Macromolecule Catabolic Process Protein Monoubiquitination Proteolysis Ubiquitin Protein Ligase Binding Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin Binding SUMO Transferase Activity Spliceosomal Complex Nuclear Speck Proteasomal Protein Catabolic Process Macromolecule Metabolic Process Establishment Of Protein Localization To Vacuole MRNA Processing Spindle Pole Identical Protein Binding Protein Metabolic Process Metal Ion Binding SnRNP Binding Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Striated Muscle Myosin Thick Filament Cytoplasm Protein Sumoylation
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