BICD2 and NEK9

Number of citations of the paper that reports this interaction (PMID 11864968)
15

Data Source:
HPRD (in vitro, in vivo)

		BICD2	NEK9
Gene Name		bicaudal D homolog 2 (Drosophila)	NIMA-related kinase 9
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytoskeleton Plasma Membrane Cytoplasmic Vesicle	Nucleus Cytosol
	Molecular Function	Protein Binding Rab GTPase Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center	Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Mitotic Nuclear Envelope Disassembly Cell Division
Pathways			Mitotic Prophase Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Envelope Breakdown Nuclear Pore Complex (NPC) Disassembly Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		5 interactors: DCTN1 DCTN2 GSK3B NEK9 RAB6A	7 interactors: BICD2 MBP NEK6 NEK7 RAN SSRP1 SUPT16H
Entrez ID		23299	91754
HPRD ID		09826	11386
Ensembl ID		ENSG00000185963	ENSG00000119638
Uniprot IDs		Q8TD16 Q96FU2	Q6PKF2 Q8TD19
PDB IDs			3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?		Melanosome Transport Pigment Granule Transport Antigen Processing And Presentation Cell Cycle Process Establishment Of Melanosome Localization Mitotic Nuclear Division Melanosome Localization Cell Cycle Cellular Pigmentation Retrograde Transport, Endosome To Golgi Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II ER-nucleus Signaling Pathway Mitotic Cell Cycle Process Pigmentation Establishment Of Localization In Cell G2/M Transition Of Mitotic Cell Cycle Microtubule-based Transport Mitotic Cell Cycle Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Immune System Process Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Response To Endoplasmic Reticulum Stress Cellular Localization Minus-end-directed Organelle Transport Along Microtubule Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Peptidyl-cysteine Methylation Establishment Of Vesicle Localization Vesicle Localization Endosomal Transport Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Antigen Processing And Presentation Of Peptide Antigen Cellular Response To Interleukin-3 Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Protein Localization To Microtubule Microtubule-based Movement Negative Regulation Of Dendrite Morphogenesis Establishment Of Organelle Localization Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Early Endosome To Golgi Transport Negative Regulation Of Cardiac Muscle Hypertrophy	Microtubule Cytoskeleton Organization Spindle Organization Organelle Organization Microtubule-based Process Positive Regulation Of Viral Transcription Transcription Elongation From RNA Polymerase II Promoter Cytoskeleton Organization Regulation Of Viral Transcription Cell Division Positive Regulation Of Viral Process Spindle Assembly DNA-templated Transcription, Elongation Viral Process Cytokinesis Ribosomal Small Subunit Export From Nucleus Defense Response To Nematode Minus-end-directed Organelle Transport Along Microtubule Regulation Of Viral Process Cellular Response To DNA Damage Stimulus Response To Nematode Ribosomal Large Subunit Export From Nucleus Cell Cycle Process Ribosomal Subunit Export From Nucleus DNA Metabolic Process DNA Replication Mitotic Nuclear Division Microtubule Anchoring At Microtubule Organizing Center Cellular Protein Complex Localization Nucleosome Disassembly Negative Regulation Of Interleukin-10 Production Cell Cycle Protein Complex Localization Regulation Of Mitotic Cell Cycle Positive Regulation Of Interleukin-4 Production Positive Regulation Of Macromolecule Biosynthetic Process Response To Mercury Ion Regulation Of Cellular Senescence Cellular Response To Stress Positive Regulation Of Gene Expression Organelle Assembly Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Interleukin-4 Production G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly Response To Stress Substantia Nigra Development Protein Export From Nucleus Androgen Receptor Signaling Pathway
Tagcloud ?		associates bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60	adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network nima p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence
Tagcloud (Difference) ?		associates bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60	adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network nima p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence
Tagcloud (Intersection) ?