CHMP6 and CHMP4A

Number of citations of the paper that reports this interaction (PMID 14505570)
292

Data Source:
HPRD (two hybrid)

		CHMP6	CHMP4A
Gene Name		charged multivesicular body protein 6	charged multivesicular body protein 4A
Image
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome	ESCRT III Complex Nucleus Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein N-terminus Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization Regulation Of Exosomal Secretion	Cell Separation After Cytokinesis Posttranslational Protein Targeting To Membrane Membrane Budding Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Protein Homooligomerization Membrane Organization Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagic Vacuole Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP4A CHMP4B ELOF1 METTL9 SNF8 VPS25 VPS36	12 interactors: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		79643	29082
HPRD ID		08564	16597
Ensembl ID		ENSG00000176108	ENSG00000254505
Uniprot IDs		Q96FZ7	Q14D22 Q9BY43
PDB IDs		2K3W 3HTU	3C3O
Enriched GO Terms of Interacting Partners?		Endosomal Transport Vacuolar Transport Negative Regulation Of Autophagic Vacuole Assembly Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Endosome Transport Via Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Organelle Late Endosome To Vacuole Transport Viral Budding Via Host ESCRT Complex Posttranslational Protein Targeting To Membrane Protein Targeting Viral Budding Protein Localization To Organelle Negative Regulation Of Macroautophagy Protein Transport Establishment Of Protein Localization Regulation Of Autophagic Vacuole Assembly Intracellular Transport Cell Separation After Cytokinesis Regulation Of Vacuole Organization Cytoplasmic Transport Protein Targeting To Vacuole Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Mitotic Metaphase Plate Congression Protein Localization Establishment Of Localization In Cell Metaphase Plate Congression Negative Regulation Of Autophagy Intracellular Protein Transport Establishment Of Chromosome Localization Cellular Localization Cellular Protein Localization Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Autophagy Protein Catabolic Process Nucleus Organization Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Maintenance Of Lens Transparency Cellular Macromolecule Catabolic Process Viral Life Cycle Regulation Of Metabolic Process	Cell Separation After Cytokinesis Cell Division Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Metaphase Plate Congression Viral Life Cycle Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Centrosome Cycle Viral Process Vacuolar Transport Mitotic Sister Chromatid Segregation Endosomal Transport Sister Chromatid Segregation Regulation Of Cell Cycle Process Nucleus Organization Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Regulation Of Mitotic Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Viral Budding Regulation Of Spindle Assembly Regulation Of Microtubule-based Process Regulation Of Mitotic Spindle Organization Membrane Organization Chromosome Segregation Regulation Of Cell Cycle Regulation Of Cell Division Regulation Of Viral Release From Host Cell Virion Assembly Cell Cycle Process Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Establishment Of Organelle Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Organelle Localization Protein Transport Establishment Of Protein Localization Regulation Of Organelle Organization Regulation Of Cytoskeleton Organization Abscission Positive Regulation Of Viral Process Membrane Budding Negative Regulation Of Cytokinesis Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Localization In Cell
Tagcloud ?		acting app bidirectional cleaving endocytosed endosomal endosomes hallmarks interruption multivesicular pool postendocytic processed recycled recycling relying rerouted retained retrieval retromer rnai secretase sequentially tgn trafficking tsg101 uncertain vps35 vps4
Tagcloud (Difference) ?		acting app bidirectional cleaving endocytosed endosomal endosomes hallmarks interruption multivesicular pool postendocytic processed recycled recycling relying rerouted retained retrieval retromer rnai secretase sequentially tgn trafficking tsg101 uncertain vps35 vps4
Tagcloud (Intersection) ?