CHMP4A and SYT17

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		CHMP4A	SYT17
Gene Name		charged multivesicular body protein 4A	synaptotagmin XVII
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Gene Ontology Annotations	Cellular Component	ESCRT III Complex Nucleus Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Trans-Golgi Network Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Transporter Activity
	Biological Process	Cell Separation After Cytokinesis Posttranslational Protein Targeting To Membrane Membrane Budding Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Protein Homooligomerization Membrane Organization Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagic Vacuole Assembly	Exocytosis
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Alcohol dependence ( 21876473)
Protein-Protein Interactions		12 interactors: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A	18 interactors: APP APTX CCDC85B CEP63 CEP70 CHMP4A FAM9B GMCL1 IKZF1 MEOX1 MEOX2 MID2 NIF3L1 NINL RUNDC3A SSX2IP TRAF2 TSC22D4
Entrez ID		29082	51760
HPRD ID		16597	17425
Ensembl ID		ENSG00000254505
Uniprot IDs		Q14D22 Q9BY43	H3BN78 H3BRH9 Q9BSW7
PDB IDs		3C3O	2ENP
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Cell Division Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Metaphase Plate Congression Viral Life Cycle Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Centrosome Cycle Viral Process Vacuolar Transport Mitotic Sister Chromatid Segregation Endosomal Transport Sister Chromatid Segregation Regulation Of Cell Cycle Process Nucleus Organization Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Regulation Of Mitotic Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Viral Budding Regulation Of Spindle Assembly Regulation Of Microtubule-based Process Regulation Of Mitotic Spindle Organization Membrane Organization Chromosome Segregation Regulation Of Cell Cycle Regulation Of Cell Division Regulation Of Viral Release From Host Cell Virion Assembly Cell Cycle Process Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Establishment Of Organelle Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Organelle Localization Protein Transport Establishment Of Protein Localization Regulation Of Organelle Organization Regulation Of Cytoskeleton Organization Abscission Positive Regulation Of Viral Process Membrane Budding Negative Regulation Of Cytokinesis Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Localization In Cell	Somite Specification Segment Specification G2/M Transition Of Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neuron Death Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Polynucleotide 3' Dephosphorylation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Mitotic Cell Cycle Somitogenesis Positive Regulation Of Transcription, DNA-templated Embryonic Pattern Specification Cell Cycle Centrosome Organization Negative Regulation Of Autophagic Vacuole Assembly Dihydrobiopterin Metabolic Process Collateral Sprouting In Absence Of Injury Somite Development Regulation Of Multicellular Organism Growth Negative Regulation Of Cellular Metabolic Process Microtubule Organizing Center Organization Sclerotome Development Response To Oxidative Stress Positive Regulation Of Macromolecule Biosynthetic Process Segmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Microtubule-based Transport Intraciliary Transport Involved In Cilium Morphogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cytoskeleton-dependent Intracellular Transport Positive Regulation Of NK T Cell Differentiation Viral Budding Via Host ESCRT Complex Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Protein Binding
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