CHMP6 and METTL9

Number of citations of the paper that reports this interaction (PubMedID 16730941)
0

Data Source:
HPRD (two hybrid)

		CHMP6	METTL9
Description		charged multivesicular body protein 6	methyltransferase 9, His-X-His N1(pi)-histidine
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GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Midbody Late Endosome Membrane Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane	Mitochondrion Endoplasmic Reticulum
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Methyltransferase Activity Transferase Activity Protein-L-histidine N-pros-methyltransferase Activity
	Biological Process	Plasma Membrane Repair Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Macroautophagy Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport Regulation Of Exosomal Secretion ESCRT III Complex Assembly	Methylation
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS			Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Serum immune biomarker levels ( 32066700) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		8 interacting genes: CHMP4A CHMP4B ELOF1 METTL9 SNCA SNF8 VPS25 VPS36	3 interacting genes: CHMP6 CHRM4 MYG1
Entrez ID		79643	51108
HPRD ID		08564	16839
Ensembl ID		ENSG00000176108	ENSG00000197006
Uniprot IDs		Q96FZ7	Q9H1A3
PDB IDs		2K3W 3HTU	7Y9C 7YF2 7YF3 7YF4 8GZE 8GZF
Enriched GO Terms of Interacting Partners?		Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway ESCRT II Complex Endosome Organization Membrane Organization Macroautophagy Vacuolar Transport Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosomal Transport Protein Localization To Vacuole Autophagy Vesicle Organization Establishment Of Protein Localization To Organelle Late Endosome Membrane Establishment Of Protein Localization To Vacuole Vesicle-mediated Transport Protein Homodimerization Activity Organelle Assembly ESCRT III Complex Amphisome Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Fusion With Vacuole Nucleus Organization Multivesicular Body-lysosome Fusion Lipid Binding Endosome Viral Budding From Plasma Membrane Lysosomal Membrane Organization Cellular Component Assembly Establishment Of Localization In Cell Organelle Organization Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Regulation Of Microtubule Cytoskeleton Organization Viral Budding Nuclear Membrane Reassembly Intracellular Protein Localization Mitotic Cytokinetic Process Protein Transport Plasma Membrane Repair Multivesicular Body Membrane Protein Targeting To ER	ESCRT III Complex Assembly G Protein-coupled Acetylcholine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity Mitochondrial Disulfide Relay System Protein-disulfide Reductase Activity Locomotory Exploration Behavior Exploration Behavior 3'-5'-RNA Exonuclease Activity Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Peptidyl-tyrosine Phosphorylation Plasma Membrane Repair Mitotic Cytokinetic Process ESCRT III Complex Regulation Of Signaling Receptor Activity Multivesicular Body Membrane Viral Budding From Plasma Membrane Negative Regulation Of Signaling Receptor Activity Multivesicular Body Organization Amphisome Membrane Late Endosome To Lysosome Transport Lysosomal Membrane Organization Vesicle Fusion With Vacuole Kinetochore Microtubule Viral Budding Regulation Of Exosomal Secretion Negative Regulation Of ERBB Signaling Pathway Vesicle Budding From Membrane Nuclear Membrane Reassembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Viral Release From Host Cell Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Tyrosine Kinase Activity Multivesicular Body Assembly Midbody Abscission Regulation Of Spindle Assembly Multivesicular Body-lysosome Fusion Regulation Of Protein Tyrosine Kinase Activity Late Endosome To Vacuole Transport Cytokinetic Process Acetylcholine Receptor Signaling Pathway Mitochondrial RNA Metabolic Process Membrane Fission Regulation Of Mitotic Spindle Organization Endosome Transport Via Multivesicular Body Sorting Pathway
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