CHMP6 and ELOF1

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP6	ELOF1
Gene Name		charged multivesicular body protein 6	elongation factor 1 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Protein Binding Protein N-terminus Binding	Metal Ion Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization Regulation Of Exosomal Secretion	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP4A CHMP4B ELOF1 METTL9 SNF8 VPS25 VPS36	7 interactors: ATP5C1 C5orf22 CHMP6 JUN KDM1A MAPK6 SUV39H1
Entrez ID		79643	84337
HPRD ID		08564	14639
Ensembl ID		ENSG00000176108	ENSG00000130165
Uniprot IDs		Q96FZ7	P60002
PDB IDs		2K3W 3HTU
Enriched GO Terms of Interacting Partners?		Endosomal Transport Vacuolar Transport Negative Regulation Of Autophagic Vacuole Assembly Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Endosome Transport Via Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Organelle Late Endosome To Vacuole Transport Viral Budding Via Host ESCRT Complex Posttranslational Protein Targeting To Membrane Protein Targeting Viral Budding Protein Localization To Organelle Negative Regulation Of Macroautophagy Protein Transport Establishment Of Protein Localization Regulation Of Autophagic Vacuole Assembly Intracellular Transport Cell Separation After Cytokinesis Regulation Of Vacuole Organization Cytoplasmic Transport Protein Targeting To Vacuole Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Mitotic Metaphase Plate Congression Protein Localization Establishment Of Localization In Cell Metaphase Plate Congression Negative Regulation Of Autophagy Intracellular Protein Transport Establishment Of Chromosome Localization Cellular Localization Cellular Protein Localization Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Autophagy Protein Catabolic Process Nucleus Organization Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Maintenance Of Lens Transparency Cellular Macromolecule Catabolic Process Viral Life Cycle Regulation Of Metabolic Process	Negative Regulation Of DNA Binding Positive Regulation Of Myeloid Cell Differentiation Regulation Of DNA Binding Cellular Response To Potassium Ion Starvation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Binding Myeloid Leukocyte Differentiation Leading Edge Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Myeloid Cell Differentiation MAPK Cascade Chromosome Organization Myeloid Cell Differentiation Positive Regulation Of Monocyte Differentiation Histone H3-K9 Dimethylation Regulation Of Binding Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Signal Transduction By Phosphorylation SMAD Protein Import Into Nucleus Rhythmic Process Positive Regulation Of Megakaryocyte Differentiation Positive Regulation By Host Of Viral Transcription Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation By Host Of Viral Transcription Histone H3-K9 Trimethylation Leukocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Dimethylation Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Gene Expression Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process Cell Cycle Microglial Cell Activation Regulation Of Monocyte Differentiation Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone Modification Chromatin Silencing At RDNA Granulocyte Differentiation Mitochondrial ATP Synthesis Coupled Proton Transport Intracellular Transport
Tagcloud ?		acting app bidirectional cleaving endocytosed endosomal endosomes hallmarks interruption multivesicular pool postendocytic processed recycled recycling relying rerouted retained retrieval retromer rnai secretase sequentially tgn trafficking tsg101 uncertain vps35 vps4
Tagcloud (Difference) ?		acting app bidirectional cleaving endocytosed endosomal endosomes hallmarks interruption multivesicular pool postendocytic processed recycled recycling relying rerouted retained retrieval retromer rnai secretase sequentially tgn trafficking tsg101 uncertain vps35 vps4
Tagcloud (Intersection) ?