CHMP4A and CDK13

Number of citations of the paper that reports this interaction (PubMedID 16730941)
0

Data Source:
HPRD (two hybrid)

		CHMP4A	CDK13
Description		charged multivesicular body protein 4A	cyclin dependent kinase 13
Image
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Multivesicular Body Membrane Amphisome Membrane	Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin K-CDK13 Complex Extracellular Region Extracellular Space Nucleus Nucleoplasm Golgi Apparatus Cytosol Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Speck Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Nucleotide Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Kinase Activity Transferase Activity Protein Kinase Binding Cyclin Binding Protein Serine Kinase Activity
	Biological Process	Plasma Membrane Repair Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Membrane Invagination Protein Transport Macroautophagy Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding From Plasma Membrane Nervous System Process Protein Polymerization Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Plasma Membrane Tubulation Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport	Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Signal Transduction Hemopoiesis Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Negative Regulation Of Stem Cell Differentiation
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	TP53 Regulates Transcription of DNA Repair Genes Neutrophil degranulation
Drugs
Diseases
GWAS			Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Plateletcrit ( 32888494) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		14 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 NTAQ1 NUTF2 PDCD6IP STAMBP SYT17 TTC19 VPS4A	9 interacting genes: C1QBP CEBPA CHMP4A KRT31 PRPF40A RNF10 SRPK2 SRSF1 TRIM7
Entrez ID		29082	8621
HPRD ID		16597	04496
Ensembl ID		ENSG00000254505	ENSG00000065883
Uniprot IDs		Q9BY43	Q14004 Q9BVE2
PDB IDs		3C3O 5MK1	5EFQ 7NXJ
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Midbody Abscission Viral Budding Mitotic Cytokinetic Process Multivesicular Body Assembly Viral Budding From Plasma Membrane Multivesicular Body Organization Endosome Organization Cytokinetic Process Mitotic Metaphase Chromosome Alignment Late Endosome To Lysosome Transport Regulation Of Mitotic Spindle Assembly Metaphase Chromosome Alignment Nuclear Membrane Reassembly Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Regulation Of Spindle Assembly Multivesicular Body-lysosome Fusion Chromosome Localization Nuclear Pore Late Endosome To Vacuole Transport Lysosomal Membrane Organization Nucleus Organization Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Sorting Pathway Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Nuclear Membrane Organization Autophagosome Maturation Kinetochore Microtubule Membrane Assembly Viral Process Multivesicular Body Membrane Vesicle Organization Vesicle Budding From Membrane Midbody Vesicle Fusion Organelle Membrane Fusion Multivesicular Body Regulation Of Centrosome Duplication Plasma Membrane Organization Lysosomal Transport Autophagosome Membrane Organelle Fusion Regulation Of Centrosome Cycle	RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Processing Regulation Of RNA Splicing MRNA Metabolic Process Macromolecule Metabolic Process RNA Metabolic Process Animal Organ Regeneration Organelle Organization Adrenergic Receptor Binding Regulation Of MRNA Metabolic Process RNA Processing RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Kininogen Binding Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Vitamin B2 C/EBP Complex Protein Localization To P-body Nucleus Organization Nuclear Speck Negative Regulation Of MRNA Metabolic Process Liver Development C5-methylcytidine-containing RNA Reader Activity Deoxyribonuclease Inhibitor Activity Negative Regulation Of MDA-5 Signaling Pathway Nucleic Acid Metabolic Process CHOP-C/EBP Complex Nuclear Matrix Regeneration White Fat Cell Proliferation Regulation Of Cell Cycle DNA Topoisomerase Binding Nuclear Speck Organization Nucleus Cytosolic Ribosome Assembly Positive Regulation Of Gene Expression Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Mitochondrial Ribosome Binding Positive Regulation Of Trophoblast Cell Migration RS Domain Binding
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