JTB and ZXDC

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		JTB	ZXDC
Gene Name		jumping translocation breakpoint	ZXD family zinc finger C
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Spindle Integral Component Of Plasma Membrane Membrane Midbody	Cellular_component Nucleus
	Molecular Function	Protein Kinase Binding	Nucleic Acid Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding LRR Domain Binding Metal Ion Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Cytokinesis Mitotic Nuclear Division Apoptotic Mitochondrial Changes Regulation Of Cell Proliferation Positive Regulation Of Protein Kinase Activity	Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP LIG3 TCEB1 ZXDC	12 interactors: APP ATXN1 CIITA JTB NR1H2 NR1H3 POGZ RORA SH3GL2 SMN1 TK1 WDR5
Entrez ID		10899	79364
HPRD ID		05240	14420
Ensembl ID		ENSG00000143543	ENSG00000070476
Uniprot IDs		O76095	Q2QGD7
PDB IDs		2KJX
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction RNA Metabolic Process Collateral Sprouting In Absence Of Injury Base-excision Repair, DNA Ligation Otolith Morphogenesis Positive Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Otolith Development Axon Choice Point Recognition Positive Regulation Of Cellular Biosynthetic Process Mitochondrial DNA Repair DNA Ligation Involved In DNA Repair Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Ligation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cellular Copper Ion Homeostasis Mitochondrial DNA Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of DNA Recombination Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Metabolic Process DNA Strand Elongation Involved In DNA Replication Mitochondrial Genome Maintenance Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity DNA Strand Elongation Mating Behavior Regulation Of Transcription Elongation From RNA Polymerase II Promoter Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Viral Transcription	Regulation Of Cholesterol Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Pinocytosis Intracellular Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Cholesterol Storage Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Cholesterol Efflux Lipid Homeostasis Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Cholesterol Transport Negative Regulation Of Macrophage Derived Foam Cell Differentiation RNA Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of Lipid Storage Regulation Of Cholesterol Efflux Regulation Of Triglyceride Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Interferon-gamma-mediated Signaling Pathway Gene Expression Regulation Of Response To Interferon-gamma Negative Regulation Of Lipid Transport Response To Steroid Hormone Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Macrophage Activation Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Regulation Of Cellular Ketone Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Endocytosis Negative Regulation Of Signal Transduction Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Cholesterol Transport Triglyceride Homeostasis Acylglycerol Homeostasis Regulation Of Triglyceride Metabolic Process Negative Regulation Of Innate Immune Response Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Signaling
Tagcloud ?		advantages assessing breakpoint comprehensive conferred consequences define hairpin hbs hbsag hbv hcc hepatocellular hepg2 jumping mitochondria motility p65 promoted regards silenced silencing stably stronger suppress transfection translocation translocations unbalanced
Tagcloud (Difference) ?		advantages assessing breakpoint comprehensive conferred consequences define hairpin hbs hbsag hbv hcc hepatocellular hepg2 jumping mitochondria motility p65 promoted regards silenced silencing stably stronger suppress transfection translocation translocations unbalanced
Tagcloud (Intersection) ?