JTB

Description		jumping translocation breakpoint
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Spindle Cytoskeleton Plasma Membrane Membrane Midbody
	Molecular Function	Protein Kinase Binding
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Apoptotic Process Apoptotic Mitochondrial Changes Regulation Of Cell Population Proliferation Positive Regulation Of Protein Kinase Activity Cell Division
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: APP ELOC LIG3 ZXDC
Entrez ID		10899
HPRD ID		05240
Ensembl ID		ENSG00000143543
Uniprot IDs		O76095
PDB IDs		2KJX
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Mitochondrial DNA Replication Negative Regulation Of Mitochondrial DNA Replication DNA Ligase (ATP) Activity Lagging Strand Elongation DNA Ligase III-XRCC1 Complex DNA Ligase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Mitochondrial DNA Metabolic Process Target-directed MiRNA Degradation Elongin Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway LRR Domain Binding Axon Choice Point Recognition Mitochondrial DNA Repair Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Double-strand Break Repair Via Alternative Nonhomologous End Joining Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Blood Circulation
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