RSG1 and IMPDH2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RSG1	IMPDH2
Gene Name		REM2 and RAB-like small GTPase 1	IMP (inosine 5-monophosphate) dehydrogenase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Ciliary Basal Body	Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	GTP Binding	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Metal Ion Binding
	Biological Process	Exocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Exocytosis Regulation Of Vesicle Fusion Cellular Protein Localization Cilium Assembly	Purine Nucleobase Metabolic Process GMP Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Small Molecule Metabolic Process Lymphocyte Proliferation Protein Homotetramerization Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process Retina Development In Camera-type Eye Cellular Response To Interleukin-4
Pathways			Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides
Drugs			NADH Mycophenolate mofetil Mycophenolic acid Ribavirin Monophosphate Nicotinamide-Adenine-Dinucleotide Selenazole-4-Carboxyamide-Adenine Dinucleotide 6-Chloropurine Riboside, 5\'-Monophosphate Inosinic Acid
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
Protein-Protein Interactions		4 interactors: FUZ IMPDH2 MSLN TMEM14C	6 interactors: AKT1 APIP PIAS4 RSG1 SUMO4 UBQLN4
Entrez ID		79363	3615
HPRD ID		14399	00895
Ensembl ID		ENSG00000132881	ENSG00000178035
Uniprot IDs		Q9BU20	P12268
PDB IDs			1B3O 1NF7 1NFB
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neural Crest Formation Positive Regulation Of Cilium Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation GMP Biosynthetic Process GMP Metabolic Process	Protein Sumoylation Glycogen Cell Differentiation Involved In Embryonic Placenta Development Protein Modification By Small Protein Conjugation Positive Regulation Of Keratinocyte Apoptotic Process L-methionine Biosynthetic Process From S-adenosylmethionine Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway Peptidyl-amino Acid Modification S-adenosylmethionine Cycle Response To UV-A Activation-induced Cell Death Of T Cells Peptidyl-lysine Modification Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus L-methionine Biosynthetic Process From Methylthioadenosine L-methionine Salvage Negative Regulation Of Fatty Acid Oxidation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Sumoylation Positive Regulation Of Glycogen Biosynthetic Process Nitric Oxide Biosynthetic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cell Size Regulation Of Apoptotic Process Methionine Biosynthetic Process Spongiotrophoblast Layer Development Negative Regulation Of Release Of Cytochrome C From Mitochondria S-adenosylmethionine Metabolic Process T Cell Apoptotic Process Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Methionine Metabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Sumoylation Insulin-like Growth Factor Receptor Signaling Pathway Sulfur Amino Acid Biosynthetic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Peripheral Nervous System Myelin Maintenance Response To Food Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Lipid Transport
Tagcloud ?			biogenesis biosynthesis dehydrogenase deoxy disrupts dually genotoxic gtp guanine inauzhin inosine inz mdm2 monophosphate notion nucleostemin pools ribonucleotide ribosomal rpl11 rpl5 rps rrna rs sirt1 stressor suppresses surprisingly
Tagcloud (Difference) ?			biogenesis biosynthesis dehydrogenase deoxy disrupts dually genotoxic gtp guanine inauzhin inosine inz mdm2 monophosphate notion nucleostemin pools ribonucleotide ribosomal rpl11 rpl5 rps rrna rs sirt1 stressor suppresses surprisingly
Tagcloud (Intersection) ?