CPLANE2 and FUZ

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		CPLANE2	FUZ
Description		ciliogenesis and planar polarity effector complex subunit 2	fuzzy planar cell polarity protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Base	Cytoplasm Cytoskeleton Cilium Cell Projection Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Endocardial Cushion Fusion Exocytosis Smoothened Signaling Pathway Intracellular Protein Localization Regulation Of Smoothened Signaling Pathway Protein Transport Protein Processing Regulation Of Exocytosis Cell Projection Organization Regulation Of Vesicle Fusion Axoneme Assembly Limb Development Cilium Assembly Cranial Skeletal System Development	Establishment Of Planar Polarity Neural Tube Closure Hair Follicle Development Negative Regulation Of Cell Population Proliferation Regulation Of Smoothened Signaling Pathway Embryonic Body Morphogenesis Protein Transport Vesicle-mediated Transport Neural Tube Development Cell Projection Organization Negative Regulation Of Cell Migration Intraciliary Transport Positive Regulation Of Cilium Assembly Embryonic Skeletal System Morphogenesis Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Neural Crest Formation Regulation Of Cilium Assembly Non-motile Cilium Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation
Pathways			Hedgehog 'off' state
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: FUZ IMPDH2 MSLN RND3 TMEM14C	2 interacting genes: CPLANE2 DSCR9
Entrez ID		79363	80199
HPRD ID		14399	08662
Ensembl ID		ENSG00000132881	ENSG00000010361
Uniprot IDs		Q9BU20	E9PK12 Q9BT04
PDB IDs			7Q3D
Enriched GO Terms of Interacting Partners?		IMP Dehydrogenase Activity Regulation Of Heme Biosynthetic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Neural Crest Formation	Regulation Of Antibacterial Peptide Production Positive Regulation Of Antibacterial Peptide Production Protein Maturation Epidermal Lamellar Body Positive Regulation Of Antimicrobial Peptide Production Cell Adhesion Involved In Heart Morphogenesis Endocardial Cushion Fusion Positive Regulation Of Antimicrobial Humoral Response Positive Regulation Of Defense Response To Bacterium Regulation Of Antimicrobial Humoral Response Regulation Of Defense Response To Bacterium Cranial Skeletal System Development Positive Regulation Of Humoral Immune Response
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