CPLANE2 and MSLN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CPLANE2	MSLN
Description		ciliogenesis and planar polarity effector complex subunit 2	mesothelin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Base	Extracellular Region Endoplasmic Reticulum Lumen Golgi Apparatus Plasma Membrane Cell Surface Membrane Side Of Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding
	Biological Process	Endocardial Cushion Fusion Exocytosis Smoothened Signaling Pathway Intracellular Protein Localization Regulation Of Smoothened Signaling Pathway Protein Transport Protein Processing Regulation Of Exocytosis Cell Projection Organization Regulation Of Vesicle Fusion Axoneme Assembly Limb Development Cilium Assembly Cranial Skeletal System Development	Cell Adhesion Cell-matrix Adhesion
Pathways			Post-translational modification: synthesis of GPI-anchored proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Amatuximab
Diseases
GWAS			Body mass index ( 26426971) Serum cancer antigen 125 (CA 125) levels ( 31666285)
Interacting Genes		5 interacting genes: FUZ IMPDH2 MSLN RND3 TMEM14C	3 interacting genes: APPBP2 CPLANE2 MUC16
Entrez ID		79363	10232
HPRD ID		14399	03030
Ensembl ID		ENSG00000132881	ENSG00000102854
Uniprot IDs		Q9BU20	Q13421
PDB IDs			4F3F 7U8C 7U9J 7UED 8CX3 8CXC 8CYH 8CZ8 8FSL 8VM1
Enriched GO Terms of Interacting Partners?		IMP Dehydrogenase Activity Regulation Of Heme Biosynthetic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Neural Crest Formation
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