THOC6

Description		THO complex subunit 6
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GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	RNA Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus Apoptotic Process Central Nervous System Development RNA Splicing MRNA Transport
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: ALYREF DDX39B PTEN
Entrez ID		79228
HPRD ID		14504
Ensembl ID		ENSG00000131652
Uniprot IDs		Q86W42
PDB IDs		7APK 7ZNK 7ZNL
Enriched GO Terms of Interacting Partners?		Transcription Export Complex RNA Export From Nucleus MRNA Export From Nucleus Osteoblast Differentiation Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Spliceosomal Complex RNA Transport MRNA Transport Nuclear Export Nucleobase-containing Compound Transport Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Nuclear Transport Nucleocytoplasmic Transport MRNA Binding C5-methylcytidine-containing RNA Reader Activity Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly ATP-dependent Protein Binding U4 SnRNA Binding Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Forebrain Morphogenesis Presynaptic Membrane Assembly U6 SnRNP ATP-dependent Activity, Acting On RNA RNA Splicing Postsynaptic Specialization Assembly Presynaptic Membrane Organization Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential Nuclear Speck MRNA Processing U4 SnRNP Locomotor Rhythm Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Maternal Behavior U6 SnRNA Binding
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