TACC3 and DRC10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TACC3	DRC10
Description		transforming acidic coiled-coil containing protein 3	dynein regulatory complex subunit 10
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GO Annotations	Cellular Component	Spindle Pole Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Cytoskeleton Centriolar Satellite Ciliary Basal Body Mitotic Spindle	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Nuclear Migration Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways		NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bladder cancer ( 20972438 24163127) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		30 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 CATSPERT CCHCR1 CDC20B CDKL5 CIB3 CLIP4 DRC10 EIF3C GDF15 KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C	1 interacting genes: TACC3
Entrez ID		10460	115811
HPRD ID		05601	13744
Ensembl ID		ENSG00000013810	ENSG00000166578
Uniprot IDs		A0A087WUE2 Q9Y6A5	Q96DY2
PDB IDs		5LXN 5LXO 5ODS 5ODT	8J07
Enriched GO Terms of Interacting Partners?		Cytoplasm Aryl Hydrocarbon Receptor Binding Aryl Hydrocarbon Receptor Complex Microtubule-based Process Mitotic Centrosome Separation Centrosome Localization Axon Hillock Centrosome Separation	Metaphase/anaphase Transition Of Cell Cycle Metaphase/anaphase Transition Of Mitotic Cell Cycle Nucleus Localization Regulation Of Mitotic Spindle Organization Nuclear Migration Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Spindle Cerebral Cortex Development Centriolar Satellite Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Sister Chromatid Segregation Regulation Of Microtubule Cytoskeleton Organization Mitotic Spindle Organization Spindle Pole Regulation Of Chromosome Segregation Regulation Of Microtubule-based Process Spindle Regulation Of Chromosome Organization Establishment Of Organelle Localization Ciliary Basal Body
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