TACC3 and TBC1D22B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TACC3	TBC1D22B
Gene Name		transforming, acidic coiled-coil containing protein 3	TBC1 domain family, member 22B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Rab GTPase Activator Activity
	Biological Process	Microtubule Cytoskeleton Organization Response To Hypoxia Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Hemopoiesis Astral Microtubule Organization Regulation Of Microtubule-based Process Cytoplasmic Sequestering Of Transcription Factor Regulation Of Cell Cycle	Positive Regulation Of Rab GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Bladder cancer ( 20972438) Urinary bladder cancer ( 20348956)
Protein-Protein Interactions		13 interactors: AKAP9 ARNT2 ASPSCR1 AURKA CDH1 CIB3 KAT2A KIZ NDEL1 SNX20 TBC1D22B TTF2 VPS37C	19 interactors: CALCOCO2 CCDC57 CCDC67 CDR2 FXR2 HSD17B14 IKZF3 KRT40 PNMA5 RBM10 SIAH1 SORBS3 TACC3 TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 VPS52
Entrez ID		10460	55633
HPRD ID		05601	15475
Ensembl ID		ENSG00000013810	ENSG00000065491
Uniprot IDs		Q9Y6A5	A8KA28 Q9NU19
PDB IDs			3DZX
Enriched GO Terms of Interacting Partners?		Mitotic Centrosome Separation Centrosome Separation Positive Regulation Of Metabolic Process Centrosome Localization In Utero Embryonic Development Cell Cycle Process Embryo Development Mitotic Cell Cycle Process Centrosome Cycle Cell Cycle Neuron Projection Extension Mitotic Cell Cycle Brain Development Mitotic Nuclear Division Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Head Development Negative Regulation Of Spindle Checkpoint Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Membrane Organization Developmental Cell Growth Positive Regulation Of Cellular Metabolic Process Centrosome Organization Spindle Assembly Involved In Female Meiosis I Pharynx Development Central Nervous System Development Blastocyst Development Microtubule Cytoskeleton Organization Forebrain Development Microtubule Organizing Center Organization Spindle Assembly Involved In Meiosis Epithelium Development Growth Protein Localization G2/M Transition Of Mitotic Cell Cycle Spindle Organization System Development Organ Development Spindle Stabilization Developmental Growth Involved In Morphogenesis Regulation Of Protein Stability Digestive Tract Development Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Growth Organelle Organization Cellular Response To Indole-3-methanol Histone H3-K14 Acetylation Positive Regulation Of Cellular Protein Catabolic Process Digestive System Development Positive Regulation Of Axon Regeneration
Tagcloud ?		acidic activating arrest centrosomal centrosome coil coiled death depletion details disrupting diverse g1 integrity lacking member p21 p38 p53 pharmacologically phosphorylated poorly require serine transforming triggered triggering tubulin vertebrates
Tagcloud (Difference) ?		acidic activating arrest centrosomal centrosome coil coiled death depletion details disrupting diverse g1 integrity lacking member p21 p38 p53 pharmacologically phosphorylated poorly require serine transforming triggered triggering tubulin vertebrates
Tagcloud (Intersection) ?