MIS12 and ZWINT

Number of citations of the paper that reports this interaction (PMID 15502821)
80

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vivo, in vitro)

		MIS12	ZWINT
Gene Name		MIS12 kinetochore complex component	ZW10 interacting kinetochore protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	MIS12/MIND Type Complex Nucleus Cytosol	Kinetochore Condensed Chromosome Kinetochore Nucleus Cytoplasm Cytosol Dendrite
	Molecular Function	Protein Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division Kinetochore Assembly	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Cell Division Establishment Of Localization In Cell
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		10 interactors: CASC5 CBX3 CBX5 DSN1 HSP90AA1 NDC80 NSL1 PMF1 SUGT1 ZWINT	9 interactors: APP CLU DSN1 LIG4 MAFB MIS12 NDC80 PHAX ZW10
Entrez ID		79003	11130
HPRD ID		12379	18366
Ensembl ID		ENSG00000167842	ENSG00000122952
Uniprot IDs		A8K1M4 Q9H081	O95229
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Division Mitotic Cell Cycle Process Mitotic Cell Cycle Chromosome Segregation Cell Cycle Process Cell Cycle Cell Division Organelle Organization Attachment Of Spindle Microtubules To Kinetochore Chromosome Organization Microtubule Anchoring Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Maintenance Of Protein Location In Cell Protein Import Into Mitochondrial Outer Membrane Chromatin Modification Maintenance Of Protein Location Maintenance Of Location In Cell Attachment Of Mitotic Spindle Microtubules To Kinetochore Chromatin Remodeling Chromatin Organization Protein Localization To Kinetochore Cell Cycle Checkpoint Protein Localization To Chromosome, Centromeric Region Histone H4-K5 Acetylation Histone H4-K8 Acetylation Chaperone-mediated Protein Complex Assembly Histone H4-K16 Acetylation Acrosome Assembly	Cell Division Chromosome Segregation Mitotic Nuclear Division Cell Cycle Mitotic Cell Cycle Process Cell Activation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Spindle Localization Neuron Apoptotic Process Neuron Death T Cell Differentiation In Thymus Central Nervous System Development Cellular Component Assembly Platelet Degranulation Organelle Organization Chromosome Organization Cell Cycle Process Mitotic Sister Chromatid Segregation Rhombomere 6 Development Positive Regulation Of Tau-protein Kinase Activity DNA Ligation Involved In DNA Recombination Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Establishment Of Localization In Cell Sister Chromatid Segregation Leukocyte Activation SnRNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Positive Regulation Of Neurofibrillary Tangle Assembly Establishment Of Cell Polarity Cellular Localization Brain Segmentation Collateral Sprouting In Absence Of Injury Cellular Macromolecular Complex Assembly Central Nervous System Myelin Maintenance Rhombomere 5 Development T Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Tau-protein Kinase Activity Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation
Tagcloud ?		assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mitosis ndc80 orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus	androgens ar arbss castration chip chromatin combining crpc crpcs deep emergence endonuclease explaining fen1 flap knock lncap overexpressing p45 pc prostatectomy reactivated sensitizes seq skp2 snai2 sublines took xenografts
Tagcloud (Difference) ?		assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mitosis ndc80 orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus	androgens ar arbss castration chip chromatin combining crpc crpcs deep emergence endonuclease explaining fen1 flap knock lncap overexpressing p45 pc prostatectomy reactivated sensitizes seq skp2 snai2 sublines took xenografts
Tagcloud (Intersection) ?