ZWINT and MAFB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ZWINT	MAFB
Gene Name		ZW10 interacting kinetochore protein	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Cytoplasm Cytosol Dendrite	Nucleus Transcription Factor Complex
	Molecular Function	Protein Binding Protein N-terminus Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Cell Division Establishment Of Localization In Cell	Transcription, DNA-templated Segment Specification Sensory Organ Development Respiratory Gaseous Exchange Rhombomere 5 Development Rhombomere 6 Development T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)	Cholesterol, total ( 20686565) Dupuytren's disease ( 21732829) LDL cholesterol ( 19060906 20686565) Obesity-related traits ( 23251661) Response to TNF antagonist treatment ( 18615156)
Protein-Protein Interactions		9 interactors: APP CLU DSN1 LIG4 MAFB MIS12 NDC80 PHAX ZW10	11 interactors: ATF4 BACH1 DDB1 FOS FOSL1 HOXD12 JUN MAF ZDHHC2 ZFP64 ZWINT
Entrez ID		11130	9935
HPRD ID		18366	07129
Ensembl ID		ENSG00000122952	ENSG00000204103
Uniprot IDs		O95229	Q9Y5Q3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Division Chromosome Segregation Mitotic Nuclear Division Cell Cycle Mitotic Cell Cycle Process Cell Activation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Spindle Localization Neuron Apoptotic Process Neuron Death T Cell Differentiation In Thymus Central Nervous System Development Cellular Component Assembly Platelet Degranulation Organelle Organization Chromosome Organization Cell Cycle Process Mitotic Sister Chromatid Segregation Rhombomere 6 Development Positive Regulation Of Tau-protein Kinase Activity DNA Ligation Involved In DNA Recombination Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Establishment Of Localization In Cell Sister Chromatid Segregation Leukocyte Activation SnRNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Positive Regulation Of Neurofibrillary Tangle Assembly Establishment Of Cell Polarity Cellular Localization Brain Segmentation Collateral Sprouting In Absence Of Injury Cellular Macromolecular Complex Assembly Central Nervous System Myelin Maintenance Rhombomere 5 Development T Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Tau-protein Kinase Activity Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Macromolecule Biosynthetic Process Cellular Response To Extracellular Stimulus Regulation Of DNA-templated Transcription In Response To Stress Macromolecule Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Gravity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Response To CAMP Positive Regulation Of Gene Expression Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Learning Response To Organophosphorus Response To Extracellular Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Purine-containing Compound Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Response To Reactive Oxygen Species Response To Corticosterone Interaction With Symbiont Regulation Of Transcription, DNA-templated Response To Mechanical Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Mineralocorticoid Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Learning Or Memory Cellular Response To Calcium Ion Response To Progesterone Positive Regulation Of Myeloid Leukocyte Differentiation Toll-like Receptor 5 Signaling Pathway Cognition Toll-like Receptor 10 Signaling Pathway Regulation Of Gene Expression SMAD Protein Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		androgens ar arbss castration chip chromatin combining crpc crpcs deep emergence endonuclease explaining fen1 flap knock lncap overexpressing p45 pc prostatectomy reactivated sensitizes seq skp2 snai2 sublines took xenografts	aminobutyric bioassay catalase cip1 cyp7a1 den deoxyguanosine diethylnitrosamine doses drinking exhibits f344 foci gaba gst hepatocarcinogenesis hydroxy modulating nrf2 placental powerful ppm sitchensis suppress suppressing transferase valerian valeriana waf1
Tagcloud (Difference) ?		androgens ar arbss castration chip chromatin combining crpc crpcs deep emergence endonuclease explaining fen1 flap knock lncap overexpressing p45 pc prostatectomy reactivated sensitizes seq skp2 snai2 sublines took xenografts	aminobutyric bioassay catalase cip1 cyp7a1 den deoxyguanosine diethylnitrosamine doses drinking exhibits f344 foci gaba gst hepatocarcinogenesis hydroxy modulating nrf2 placental powerful ppm sitchensis suppress suppressing transferase valerian valeriana waf1
Tagcloud (Intersection) ?