ZWINT and ZW10

Number of citations of the paper that reports this interaction (PMID 15824131)
62

Data Source:
HPRD (in vivo, in vitro)

		ZWINT	ZW10
Gene Name		ZW10 interacting kinetochore protein	zw10 kinetochore protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Cytoplasm Cytosol Dendrite	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Kinetochore Microtubule Cytosol Membrane
	Molecular Function	Protein Binding Protein N-terminus Binding	Protein Binding Centromeric DNA Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Cell Division Establishment Of Localization In Cell	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Protein Complex Assembly ER To Golgi Vesicle-mediated Transport Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Regulation Of Exit From Mitosis Meiotic Nuclear Division Protein Transport Protein Localization To Kinetochore Cell Division
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		9 interactors: APP CLU DSN1 LIG4 MAFB MIS12 NDC80 PHAX ZW10	7 interactors: APP DCTN2 PTF1A RINT1 UBC ZWILCH ZWINT
Entrez ID		11130	9183
HPRD ID		18366	04902
Ensembl ID		ENSG00000122952	ENSG00000086827
Uniprot IDs		O95229	A1A528 O43264
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Division Chromosome Segregation Mitotic Nuclear Division Cell Cycle Mitotic Cell Cycle Process Cell Activation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Spindle Localization Neuron Apoptotic Process Neuron Death T Cell Differentiation In Thymus Central Nervous System Development Cellular Component Assembly Platelet Degranulation Organelle Organization Chromosome Organization Cell Cycle Process Mitotic Sister Chromatid Segregation Rhombomere 6 Development Positive Regulation Of Tau-protein Kinase Activity DNA Ligation Involved In DNA Recombination Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Establishment Of Localization In Cell Sister Chromatid Segregation Leukocyte Activation SnRNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Positive Regulation Of Neurofibrillary Tangle Assembly Establishment Of Cell Polarity Cellular Localization Brain Segmentation Collateral Sprouting In Absence Of Injury Cellular Macromolecular Complex Assembly Central Nervous System Myelin Maintenance Rhombomere 5 Development T Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Tau-protein Kinase Activity Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Mitotic Cell Cycle Checkpoint Cell Cycle Intracellular Receptor Signaling Pathway Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Mitotic Nuclear Division Establishment Of Localization In Cell Cell Cycle Process Cellular Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Cycle Regulation Of ERBB Signaling Pathway Regulation Of Cell Cycle Process Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Neural Retina Development Collateral Sprouting Axon Midline Choice Point Recognition Amacrine Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Axon Choice Point Recognition Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Phase Transition Neuron Remodeling Exocrine Pancreas Development Positive Regulation Of Cell Cycle Antigen Processing And Presentation Positive Regulation Of Proteolysis Viral Protein Processing Regulation Of DNA Damage Checkpoint Regulation Of ER To Golgi Vesicle-mediated Transport
Tagcloud ?		androgens ar arbss castration chip chromatin combining crpc crpcs deep emergence endonuclease explaining fen1 flap knock lncap overexpressing p45 pc prostatectomy reactivated sensitizes seq skp2 snai2 sublines took xenografts	apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde rint1 sec39 summarize tethering tip20 trafficking transport vesicle
Tagcloud (Difference) ?		androgens ar arbss castration chip chromatin combining crpc crpcs deep emergence endonuclease explaining fen1 flap knock lncap overexpressing p45 pc prostatectomy reactivated sensitizes seq skp2 snai2 sublines took xenografts	apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde rint1 sec39 summarize tethering tip20 trafficking transport vesicle
Tagcloud (Intersection) ?