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PRR14 and SH3BP4
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
PRR14
SH3BP4
Gene Name
proline rich 14
SH3-domain binding protein 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Coated Pit
Clathrin-coated Vesicle
Extracellular Vesicular Exosome
Molecular Function
GDP-dissociation Inhibitor Activity
Protein Binding
Ras GTPase Binding
Identical Protein Binding
Biological Process
Endocytosis
Negative Regulation Of Cell Proliferation
Positive Regulation Of Autophagy
Negative Regulation Of Cell Growth
Negative Regulation Of TOR Signaling
Negative Regulation Of GTPase Activity
Amino Acid Import
Regulation Of Catalytic Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Pathways
Drugs
Diseases
GWAS
Dialysis-related mortality (
21546767
)
Orofacial clefts (
22419666
)
Protein-Protein Interactions
4 interactors:
APP
CBX5
SH3BP4
SH3GL2
21 interactors:
C2orf73
CCT3
CEP78
CIZ1
DNAJA4
FKBP4
GAPDHS
GKAP1
HSPA5
MPHOSPH8
MRGBP
NFU1
PLEKHA1
PRR14
PSMA1
TCP1
TTC1
TXNL1
YWHAE
YWHAG
ZBTB37
Entrez ID
78994
23677
HPRD ID
14541
09285
Ensembl ID
ENSG00000156858
ENSG00000130147
Uniprot IDs
Q9BWN1
Q9P0V3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Endocytosis
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Collateral Sprouting
Axon Midline Choice Point Recognition
Vesicle-mediated Transport
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Neuron Remodeling
Axon Guidance
Negative Regulation Of Hydrolase Activity
Blood Coagulation
Hemostasis
Protein Localization To Lysosome
Axonogenesis
Cellular Copper Ion Homeostasis
Axon Development
Regulation Of Body Fluid Levels
Cell Morphogenesis Involved In Neuron Differentiation
Wound Healing
Chemotaxis
Copper Ion Homeostasis
Suckling Behavior
Regulation Of Growth
Cellular Localization
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Neuron Projection Morphogenesis
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Response To Wounding
Regulation Of Receptor Internalization
Cell Morphogenesis Involved In Differentiation
Negative Regulation Of TOR Signaling
Mating Behavior
Negative Regulation Of GTPase Activity
Regulation Of Signal Transduction
Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of Autophagy
Synaptic Vesicle Endocytosis
RNA Polyadenylation
Neuron Recognition
Negative Regulation Of Catalytic Activity
Synaptic Vesicle Recycling
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Neuron Projection Development
Cell Projection Morphogenesis
Ionotropic Glutamate Receptor Signaling Pathway
Protein Folding
Toxin Transport
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Response To Heat
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Cellular Response To Heat
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Binding Of Sperm To Zona Pellucida
Protein Localization
Substantia Nigra Development
Response To Temperature Stimulus
Sperm-egg Recognition
Steroid Hormone Receptor Complex Assembly
Regulation Of Protein Folding In Endoplasmic Reticulum
Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm
Neural Nucleus Development
'de Novo' Posttranslational Protein Folding
Positive Regulation Of Mitochondrion Organization
'de Novo' Protein Folding
Cell-cell Recognition
Cellular Response To Heat
Negative Regulation Of Peptidyl-serine Dephosphorylation
Cerebellum Structural Organization
Regulation Of Heart Rate By Hormone
Mitotic Cell Cycle Process
Midbrain Development
Positive Regulation Of DNA-dependent DNA Replication Initiation
Mitotic Cell Cycle
Regulation Of Mitochondrion Organization
Cell Recognition
Single Fertilization
Regulation Of Apoptotic Process
Negative Regulation Of Protein Dephosphorylation
Positive Regulation Of Protein Ubiquitination
Regulation Of DNA-dependent DNA Replication Initiation
Cellular Response To Stress
Maintenance Of Protein Location In Cell
Regulation Of Cell Death
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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