PRR14 and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		PRR14	SH3BP4
Description		proline rich 14	SH3 domain binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Lamina Nucleoplasm Chromosome	Nucleus Cytoplasm Clathrin-coated Pit Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Muscle Organ Development	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis ( 28025584) Irritable mood ( 29500382) Lymphocyte count ( 32888494) Multiple myeloma ( 33875642) Neurociticism ( 29500382)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 34099189) Schizophrenia x sex interaction ( 34099189) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		5 interacting genes: APP CBX5 CRK SH3BP4 SH3GL2	23 interacting genes: CCT3 CEP78 CFTR CIMIP6 CIZ1 DNAJA4 EPS15 FKBP4 GAPDHS GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 SNCA TCP1 TTC1 TXNL1 YWHAG ZBTB37
Entrez ID		78994	23677
HPRD ID		14541	09285
Ensembl ID		ENSG00000156858	ENSG00000130147
Uniprot IDs		Q9BWN1	Q9P0V3
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Nerve Growth Factor Cellular Response To Nerve Growth Factor Stimulus Response To Yeast Ephrin Receptor Binding Identical Protein Binding Response To Growth Factor Cellular Response To Growth Factor Stimulus Dendrite Development Regulation Of T Cell Migration Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Lymphocyte Migration Endocytosis Clathrin-coated Pit Response To Fungus Regulation Of Receptor Internalization DTTP Catabolic Process DCTP Diphosphatase Activity DCTP Catabolic Process Neuron Projection Development Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Growth Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Lipoprotein Particle Regulation Of Mononuclear Cell Migration Import Into Cell Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Developmental Cell Growth Microglia Development Developmental Growth Involved In Morphogenesis Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of MAPK Cascade Helper T Cell Diapedesis Regulation Of GTPase Activity Cerebellar Neuron Development Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Negative Regulation Of Blood-brain Barrier Permeability Amino Acid Import	Protein Folding Unfolded Protein Binding ATP-dependent Protein Folding Chaperone Cytosol Protein Folding Chaperone Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Zona Pellucida Receptor Complex Chaperonin-containing T-complex Heat Shock Protein Binding Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Receptor Recycling Negative Regulation Of Microtubule Polymerization Protein-folding Chaperone Binding Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of Receptor Recycling Positive Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Refolding Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Steroid Hormone Receptor Complex Assembly Negative Regulation Of Protein-containing Complex Assembly Phosphoprotein Binding Regulation Of Protein Folding In Endoplasmic Reticulum Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Binding Of Sperm To Zona Pellucida Sperm-egg Recognition H4/H2A Histone Acetyltransferase Complex ATP Hydrolysis Activity Negative Regulation Of Microtubule Polymerization Or Depolymerization Tau Protein Binding Maintenance Of Protein Localization In Organelle Regulation Of Protein Stability Protein Sequestering Activity Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process
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