SLBP and LSM10

Number of citations of the paper that reports this interaction (PMID 10207079)
59

Data Source:
HPRD (in vivo)

		SLBP	LSM10
Gene Name		stem-loop binding protein	LSM10, U7 small nuclear RNA associated
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Ribonucleoprotein Complex Histone Pre-mRNA 3'end Processing Complex	Nucleus Nucleoplasm U7 SnRNP Cajal Body
	Molecular Function	MRNA Binding Protein Binding Poly(A) RNA Binding Histone Pre-mRNA Stem-loop Binding Histone Pre-mRNA DCP Binding	Protein Binding Histone Pre-mRNA DCP Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA 3'-end Processing MRNA Export From Nucleus Histone MRNA Metabolic Process Gene Expression MRNA 3'-end Processing Nuclear DNA Replication MRNA Transport	Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA RNA Polymerase II Transcription Transport of Mature mRNAs Derived from Intronless Transcripts Processing of Capped Intronless Pre-mRNA Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination	SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination SLBP independent Processing of Histone Pre-mRNAs
Drugs
Diseases
GWAS		Urinary bladder cancer ( 20348956)
Protein-Protein Interactions		6 interactors: CDK4 CDK6 ERI1 LSM10 USP8 ZNF473	6 interactors: BMPR2 CLNS1A LSM11 LSM3 SLBP SMN1
Entrez ID		7884	84967
HPRD ID		03884	14326
Ensembl ID		ENSG00000163950	ENSG00000181817
Uniprot IDs		E7EUV9 Q14493 Q53XR2	Q969L4
PDB IDs		2KJM 4L8R
Enriched GO Terms of Interacting Partners?		RNA 3'-end Processing Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cell Division Positive Regulation Of Fibroblast Proliferation DNA-templated Transcription, Termination MRNA 3'-end Processing Regulation Of Fibroblast Proliferation Cell Dedifferentiation RNA Processing Positive Regulation Of Mitotic Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Cell Cycle Histone MRNA 3'-end Processing Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Process RRNA 3'-end Processing Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Negative Regulation Of Cellular Senescence Positive Regulation Of Cell Size Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Cell Cycle Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Aging Protein K48-linked Deubiquitination Regulation Of Mitotic Cell Cycle Protein K63-linked Deubiquitination Dentate Gyrus Development Maturation Of 5.8S RRNA MRNA Processing Type B Pancreatic Cell Development Negative Regulation Of Cell Cycle Astrocyte Development Type B Pancreatic Cell Differentiation Negative Regulation Of Cell Cycle Arrest Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Lateral Ventricle Development Enteroendocrine Cell Differentiation Cellular Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	MRNA Processing MRNA Metabolic Process RNA Processing Histone MRNA 3'-end Processing RNA Metabolic Process Gene Expression Histone MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Spliceosomal SnRNP Assembly Nucleobase-containing Compound Metabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination Nitrogen Compound Metabolic Process MRNA 3'-end Processing RNA 3'-end Processing Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Vasoconstriction Ribonucleoprotein Complex Assembly Transcription From RNA Polymerase II Promoter Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation Ribonucleoprotein Complex Biogenesis Lymphangiogenesis Lymph Vessel Morphogenesis Regulation Of Axon Extension Involved In Axon Guidance Venous Blood Vessel Development NcRNA Metabolic Process Retina Vasculature Development In Camera-type Eye Lymph Vessel Development Negative Regulation Of Systemic Arterial Blood Pressure Nuclear DNA Replication Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Cell Cycle G1/S Phase Transition Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cell Volume Homeostasis Activin Receptor Signaling Pathway Chondrocyte Development Positive Regulation Of BMP Signaling Pathway
Tagcloud ?		arsenic canonical carcinogenesis carcinogenic chromosomes continued display dramatically end excess histones instability instead loop messenger metazoan missing mitosis mrnas notably poly polyadenylated polyadenylation possibly proteasomal stem susceptible tail terminate	altering analogous arrested captured chase coordinated elimination h2a h2b h3f3b hela hn hnrnp nonpolyadenylated nontransformed oligonucleotide posttranscriptional precisely replication repress restricts ribonucleoprotein rnp snrna snrnp spectrometric tightly u7 ul1
Tagcloud (Difference) ?		arsenic canonical carcinogenesis carcinogenic chromosomes continued display dramatically end excess histones instability instead loop messenger metazoan missing mitosis mrnas notably poly polyadenylated polyadenylation possibly proteasomal stem susceptible tail terminate	altering analogous arrested captured chase coordinated elimination h2a h2b h3f3b hela hn hnrnp nonpolyadenylated nontransformed oligonucleotide posttranscriptional precisely replication repress restricts ribonucleoprotein rnp snrna snrnp spectrometric tightly u7 ul1
Tagcloud (Intersection) ?