LSM10 and LSM11

Number of citations of the paper that reports this interaction (PubMedID 12975319)
45

Data Source:
HPRD (in vivo, in vitro)

		LSM10	LSM11
Description		LSM10, U7 small nuclear RNA associated	LSM11, U7 small nuclear RNA associated
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U7 SnRNP Cajal Body Nuclear Body Cytoplasmic U SnRNP Body Ribonucleoprotein Complex	Nucleus Nucleoplasm U7 SnRNP Telomerase Holoenzyme Complex Nuclear Body Histone Pre-mRNA 3'end Processing Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding	RNA Binding Protein Binding U7 SnRNA Binding
	Biological Process	MRNA Processing MRNA 3'-end Processing By Stem-loop Binding And Cleavage RNA Splicing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	MRNA Processing MRNA 3'-end Processing By Stem-loop Binding And Cleavage Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Chromatin Organization
Pathways		SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Diverticulitis ( 28585551) Neutrophil count ( 29403010)	Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		10 interacting genes: BMPR2 CLNS1A LSM11 LSM3 MIR10B MIR128-1 MIR20A MIRLET7A1 SLBP SMN1	9 interacting genes: LSM10 MIR10B MIR128-1 MIR20A MIRLET7A1 RAB19 SMN1 SNRPB ZNF473
Entrez ID		84967	134353
HPRD ID		14326	11289
Ensembl ID		ENSG00000181817	ENSG00000155858
Uniprot IDs		Q969L4	P83369
PDB IDs		6V4X	6V4X 8G1U
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Positive Regulation Of MRNA Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulatory NcRNA-mediated Gene Silencing MRNA Processing Negative Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex MRNA Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Proliferation Involved In Heart Morphogenesis MRNA 3'-UTR Binding RNA Processing Regulation Of Translation Histone MRNA Metabolic Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Cell Migration Regulation Of Cell Motility MRNA 3'-end Processing Regulation Of Endothelial Cell Migration Regulation Of MRNA Stability Regulation Of Locomotion RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process Post-transcriptional Regulation Of Gene Expression Spliceosomal SnRNP Assembly Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Outflow Tract Morphogenesis Negative Regulation Of Lipoprotein Transport Negative Regulation Of Cardioblast Proliferation RNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Osteoblast Differentiation Extracellular Space Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility	MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Regulatory NcRNA-mediated Gene Silencing Histone Pre-mRNA DCP Binding Negative Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis MRNA 3'-end Processing By Stem-loop Binding And Cleavage Cajal Body U7 SnRNP MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration SMN-Sm Protein Complex MRNA 3'-UTR Binding Regulation Of Translation MRNA Processing Positive Regulation Of MRNA Metabolic Process Histone MRNA Metabolic Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of MRNA Stability Regulation Of Endothelial Cell Migration MRNA 3'-end Processing Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Negative Regulation Of Blood Vessel Endothelial Cell Migration Cytoplasmic U SnRNP Body Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Lipoprotein Transport Negative Regulation Of Cardioblast Proliferation RNA Processing Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Endothelial Cell Migration RNA Splicing Negative Regulation Of Locomotion RNA 3'-end Processing Extracellular Vesicle U2 SnRNP Binding Regulation Of Cell Migration
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