SLBP

Gene Name		stem-loop binding protein
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Ribonucleoprotein Complex Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	MRNA Binding Protein Binding Poly(A) RNA Binding Histone Pre-mRNA Stem-loop Binding Histone Pre-mRNA DCP Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA 3'-end Processing MRNA Export From Nucleus Histone MRNA Metabolic Process Gene Expression MRNA 3'-end Processing Nuclear DNA Replication MRNA Transport
Pathways		SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA RNA Polymerase II Transcription Transport of Mature mRNAs Derived from Intronless Transcripts Processing of Capped Intronless Pre-mRNA Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Urinary bladder cancer ( 20348956)
Protein-protein Interactions		6 interactors: CDK4 CDK6 ERI1 LSM10 USP8 ZNF473
Entrez ID		7884
HPRD ID		03884
Ensembl ID		ENSG00000163950
Uniprot IDs		E7EUV9 Q14493 Q53XR2
PDB IDs		2KJM 4L8R
Enriched GO Terms of Interacting Partners?		RNA 3'-end Processing Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cell Division Positive Regulation Of Fibroblast Proliferation DNA-templated Transcription, Termination MRNA 3'-end Processing Regulation Of Fibroblast Proliferation Cell Dedifferentiation RNA Processing Positive Regulation Of Mitotic Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Cell Cycle Histone MRNA 3'-end Processing Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Process RRNA 3'-end Processing Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Negative Regulation Of Cellular Senescence Positive Regulation Of Cell Size Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Cell Cycle Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Aging Protein K48-linked Deubiquitination Regulation Of Mitotic Cell Cycle Protein K63-linked Deubiquitination Dentate Gyrus Development Maturation Of 5.8S RRNA MRNA Processing Type B Pancreatic Cell Development Negative Regulation Of Cell Cycle Astrocyte Development Type B Pancreatic Cell Differentiation Negative Regulation Of Cell Cycle Arrest Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Lateral Ventricle Development Enteroendocrine Cell Differentiation Cellular Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Tagcloud ?		arsenic canonical carcinogenesis carcinogenic chromosomes continued display dramatically end excess histones instability instead loop messenger metazoan missing mitosis mrnas notably poly polyadenylated polyadenylation possibly proteasomal stem susceptible tail terminate