ZNF184 and CLIC1

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		ZNF184	CLIC1
Name		zinc finger protein 184	chloride intracellular channel 1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Endoplasmic Reticulum Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Monoatomic Ion Channel Complex Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Chloride Channel Activity Protein Binding Oxidoreductase Activity Cadherin Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Monoatomic Ion Transport Chloride Transport Signal Transduction Monoatomic Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Mitochondrial Membrane Potential Platelet Aggregation Chloride Transmembrane Transport
Pathways		Generic Transcription Pathway	None
Drugs		None	Copper Artenimol
GWAS		Apolipoprotein A1 levels ( 32203549 ) Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Body size at age 10 ( 32376654 ) Brain morphology (MOSTest) ( 32665545 ) FEV1 ( 30804560 ) Fish- and plant-related diet ( 32066663 ) Hemoglobin levels ( 32327693 ) Liver iron content ( 34128465 ) Lung adenocarcinoma ( 28604730 ) Lung cancer ( 28604730 ) Lung cancer in ever smokers ( 28604730 ) Lung function (FEV1/FVC) ( 30804560 ) Lung function (FVC) ( 30804560 ) Lung function (low FEV1 vs high FEV1) ( 26423011 ) Modic changes ( 30808802 ) Parkinson's disease ( 28892059 27182965 ) Peak expiratory flow ( 30804560 ) Refractive error ( 32231278 ) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848 ) Schizophrenia ( 19571809 ) Squamous cell lung carcinoma ( 28604730 ) Subcortical volume (MOSTest) ( 32665545 ) Systemic lupus erythematosus ( 24871463 ) Triglyceride levels ( 32203549 )	Adult body size ( 32376654 ) Asthma ( 31619474 ) Asthma (childhood onset) ( 31619474 ) Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Inflammatory bowel disease ( 28067908 ) Mean platelet volume ( 27863252 ) Ulcerative colitis ( 28067908 )
Novel Interactors		None recorded	2 novel interactors: DNAJC19 PCSK5
Interacting Genes		4 interacting genes: CLIC1 EWSR1 SOX6 UBP1	25 interacting genes: AKAP9 ALOX5AP ANXA1 ATP5PB ATP6V0A1 ATP6V0C CEBPA CFTR CPT1A IKBKG LSM1 MEOX2 MYOC NHSL2 NTF4 NUP62 PRDX4 PSMD10 RPLP1 SUMO4 THRA TPRN TRAPPC2 ZNF184 ZNF302
Entrez ID		7738	1192
HPRD ID		03785	04188
Ensembl ID		ENSG00000096654	ENSG00000213719
Uniprot IDs		Q99676	O00299 Q53FB0 Q5SRT3
PDB IDs		Not available	1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA 4JZQ 4K0G 4K0N 7F8R 7FBQ