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CA9 and CDH1
Number of citations of the paper that reports this interaction (PubMedID
14567991
)
0
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, in vivo)
CA9
CDH1
Description
carbonic anhydrase 9
cadherin 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleolus
Plasma Membrane
Membrane
Basolateral Plasma Membrane
Microvillus Membrane
Cell Projection
Extracellular Region
Cytoplasm
Endosome
Golgi Apparatus
Trans-Golgi Network
Plasma Membrane
Adherens Junction
Cytoplasmic Side Of Plasma Membrane
Actin Cytoskeleton
Membrane
Lateral Plasma Membrane
Catenin Complex
Flotillin Complex
Lamellipodium
Cell Junction
Desmosome
Cortical Actin Cytoskeleton
Apical Junction Complex
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Anchoring Junction
Postsynapse
Glutamatergic Synapse
Molecular Function
Carbonate Dehydratase Activity
Protein Binding
Zinc Ion Binding
Lyase Activity
Metal Ion Binding
Molecular Function Activator Activity
Calcium Ion Binding
Protein Binding
Beta-catenin Binding
Ankyrin Binding
GTPase Activating Protein Binding
Identical Protein Binding
Gamma-catenin Binding
Cadherin Binding
Metal Ion Binding
Cell Adhesion Molecule Binding
Cell-cell Adhesion Mediator Activity
Protein Tyrosine Kinase Binding
Biological Process
Response To Hypoxia
Morphogenesis Of An Epithelium
Response To Xenobiotic Stimulus
Response To Testosterone
Secretion
Cell Morphogenesis
Desmosome Assembly
Cell-cell Junction Assembly
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Synapse Assembly
Response To Xenobiotic Stimulus
Response To Toxic Substance
Regulation Of Gene Expression
Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Cell Migration
Pituitary Gland Development
Negative Regulation Of Cell-cell Adhesion
Negative Regulation Of Cell Migration
Negative Regulation Of Axon Extension
Neuron Projection Development
Cell Junction Assembly
Adherens Junction Organization
Positive Regulation Of Protein Import Into Nucleus
Cell-cell Adhesion Mediated By Cadherin
Positive Regulation Of DNA-templated Transcription
Regulation Of Transport
Cellular Response To Lithium Ion
Response To Heparin
Cellular Response To Indole-3-methanol
Protein Localization To Plasma Membrane
Cell-cell Adhesion
Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission
Response To Gram-positive Bacterium
Positive Regulation Of Protein Localization
Pathways
Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxide
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Integrin cell surface interactions
Apoptotic cleavage of cell adhesion proteins
Adherens junctions interactions
RHO GTPases activate IQGAPs
InlA-mediated entry of Listeria monocytogenes into host cells
Regulation of CDH1 Function
Regulation of CDH1 mRNA translation by microRNAs
Degradation of CDH1
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
Formation of definitive endoderm
Transcriptional and post-translational regulation of MITF-M expression and activity
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Myoepithelial Cells
Developmental Lineage of Mammary Stem Cells
Drugs
Benzthiazide
Benzthiazide
Cyclothiazide
Hydroflumethiazide
Zonisamide
Girentuximab
Ellagic acid
Sodium carbonate
DTP-348
Diseases
Penile cancer
Breast cancer
Gastric cancer
Nasopharyngeal cancer
Hepatocellular carcinoma
Thyroid cancer
GWAS
Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease (
34020725
)
Colorectal cancer (
19011631
)
Colorectal cancer or advanced adenoma (
30510241
)
Cutaneous malignant melanoma (
26237428
32341527
)
Glycated hemoglobin levels (
34059833
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
32888494
)
Late-onset Alzheimer's disease (
27770636
)
Mean corpuscular hemoglobin (
27863252
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Nevus count or cutaneous melanoma (
32341527
)
Red cell distribution width (
32888494
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Ulcerative colitis (
19915572
)
Interacting Genes
6 interacting genes:
CAND1
CDH1
CSRP1
CTNNA1
CTNNB1
GLRX3
74 interacting genes:
ACTR3
AKT1
ANAPC7
AOPEP
ARHGAP32
ARVCF
AURKB
CA9
CASP3
CASP8
CBLL1
CCNB1
CDC42
CDK8
CHEK1
CSE1L
CSNK2A1
CTNNA1
CTNNB1
CTNND1
CTNND2
DNMT3A
EGFR
ERBIN
EZR
FADD
FARP2
FER
FGFR1
FYN
GALNT12
GNA12
GNA13
GSK3B
HDAC1
HDAC2
HEMGN
HRAS
HSD17B3
IQGAP1
IRS1
ITGAE
ITGB7
JUP
KEAP1
MAD2L2
MAP2K1
MAPK3
MKI67
MSANTD3
MYO6
NANS
NDRG1
NEDD9
NFE2L2
PIP5K1C
PKD1
PKP4
PPP1CA
PSEN1
PTPN14
PTPRF
PTPRM
PTTG1
RAB8B
RRM2
SFRP2
STX17
TMOD1
UCA1
UCHL3
VCL
YES1
ZNF510
Entrez ID
768
999
HPRD ID
04417
01885
Ensembl ID
ENSG00000107159
ENSG00000039068
Uniprot IDs
A0A0S2Z341
A0A0S2Z3D0
Q16790
A0A0U2ZQU7
B3GN61
P12830
Q9UII7
PDB IDs
2HKF
3IAI
5DVX
5FL4
5FL5
5FL6
6FE0
6FE1
6FE2
6G98
6G9U
6QN2
6QN5
6QN6
6QUT
6RQN
6RQQ
6RQU
6RQW
6TL5
6TL6
6Y74
7POM
8CO0
8Q18
8Q19
8Q1A
1O6S
2O72
2OMT
2OMU
2OMV
2OMX
2OMY
2OMZ
3FF7
3FF8
3L6X
3L6Y
4ZT1
4ZTE
6CXY
6OLE
6OLF
6OLG
6VEL
7STZ
8H62
Enriched GO Terms of Interacting Partners
?
Cellular Response To Indole-3-methanol
Response To Indole-3-methanol
Flotillin Complex
Catenin Complex
Negative Regulation Of Cell Development
Gamma-catenin Binding
Cell-cell Junction Assembly
Negative Regulation Of Neurogenesis
Z Disc
Negative Regulation Of Nervous System Development
Cell-cell Adhesion
Regulation Of Protein Localization To Nucleus
Negative Regulation Of Multicellular Organismal Process
Cell-cell Junction Organization
Regulation Of Protein Sumoylation
Adherens Junction
Lamellipodium
Disordered Domain Specific Binding
Cell Junction
Apical Junction Complex
Negative Regulation Of Cell Differentiation
Cell-cell Adhesion Mediated By Cadherin
Response To Alcohol
Cell Junction Assembly
Regulation Of Neuroblast Proliferation
Neuroblast Proliferation
Intercalated Disc
Regulation Of Cell Development
Cadherin Binding
Cell Adhesion
Adherens Junction Organization
Cellular Response To Oxygen-containing Compound
Apoptotic Signaling Pathway
Regulation Of Protein Localization
Negative Regulation Of Developmental Process
Lateral Plasma Membrane
Regulation Of Neurogenesis
Odontogenesis Of Dentin-containing Tooth
Ligase Inhibitor Activity
Glial Cell Fate Determination
Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation
Anchoring Junction
Focal Adhesion
Regulation Of Nervous System Development
Negative Regulation Of Post-translational Protein Modification
Beta-catenin Binding
Regulation Of Cell-cell Adhesion
Positive Regulation Of Protein Localization To Nucleus
Cell Junction Organization
Epidermal Cell Differentiation
Cell-cell Adhesion
Adherens Junction
Cell Adhesion
Regulation Of Cell Motility
Regulation Of Cell Migration
Regulation Of Locomotion
Cell Surface Receptor Signaling Pathway
Cytoplasm
Focal Adhesion
Cadherin Binding
Regulation Of Intracellular Signal Transduction
Regulation Of Cellular Component Organization
Enzyme-linked Receptor Protein Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Cell-cell Junction
Regulation Of Signal Transduction
Intracellular Signal Transduction
Signal Transduction
Anchoring Junction
Regulation Of Signaling
Regulation Of Cell Communication
Plasma Membrane
Regulation Of Apoptotic Signaling Pathway
Regulation Of Cell Projection Organization
Regulation Of Mitotic Cell Cycle
Response To Xenobiotic Stimulus
Cell Cortex
Negative Regulation Of Apoptotic Signaling Pathway
Anatomical Structure Morphogenesis
Regulation Of Protein Catabolic Process
Regulation Of Cell Adhesion
Regulation Of Protein Metabolic Process
Positive Regulation Of Cell Migration
Cell Motility
Regulation Of Cell Population Proliferation
Positive Regulation Of Signaling
Regulation Of Multicellular Organismal Process
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Cycle
Nucleus
Positive Regulation Of Cell Motility
Negative Regulation Of Cell Motility
Cytosol
Cytoskeleton
Positive Regulation Of Locomotion
ERBB Signaling Pathway
Cell Migration
Positive Regulation Of Signal Transduction
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Cellular Component Organization
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Tagcloud (Difference)
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Tagcloud (Intersection)
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