LRCH4 and CA8

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		LRCH4	CA8
Name		leucine rich repeats and calponin homology domain containing 4	carbonic anhydrase 8
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane PML Body	Cytoplasm
	Molecular Function	Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Membrane Raft Assembly Nervous System Development Positive Regulation Of Toll-like Receptor Signaling Pathway	Positive Regulation Of Calcium-mediated Signaling
Drugs		None	Zonisamide
GWAS		Brain morphology (MOSTest) ( 32665545 ) Macular thickness ( 30535121 ) Subcortical volume (MOSTest) ( 32665545 )	Adult body size ( 32376654 ) Blood protein levels ( 30072576 ) Cardiac hypertrophy ( 21348951 ) Free thyroxine concentration ( 30367059 ) Height ( 31562340 ) Hemoglobin ( 32888494 ) High myopia ( 33830181 ) Myopia ( 27182965 ) Obesity-related traits ( 23251661 ) Parkinson's disease ( 27182965 ) Red blood cell count ( 32888494 ) Refractive error ( 32231278 ) Response to amphetamines ( 22952603 ) Schizophrenia ( 29483656 28991256 30285260 25056061 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 )
Novel Interactors		1 novel interactors: PRKAR2B	None recorded
Interacting Genes		16 interacting genes: CA8 CYB5R3 ELOVL7 HSD17B11 KASH5 KRT40 KRTAP10-7 KRTAP10-8 MDFI NOTCH2NLA RBBP6 RETREG3 RNASEK RTN4 SIN3A SPOP	14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3
Entrez ID		4034	767
HPRD ID		10062	00266
Ensembl ID		ENSG00000077454	ENSG00000178538
Uniprot IDs		B4DYF8 H7C5D9 O75427	P35219
PDB IDs		Not available	2W2J
GO Terms Enriched among Interactors		Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Keratin Filament	None