ZNF41 and TLX3

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZNF41	TLX3
Gene Name		zinc finger protein 41	T-cell leukemia homeobox 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Neurological System Process Regulation Of Transcription, DNA-templated Central Nervous System Development Respiratory Gaseous Exchange Negative Regulation Of Neuron Differentiation Neuron Fate Specification
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: FAM9B KRTAP10-7 SMAD2 TLX3	16 interactors: DENND4A GTF2A1L HIST1H2BJ HNRNPUL1 HOPX ING4 IRF9 LMO2 MEIS1 PPP1CC PQBP1 SNTA1 SP1 TLE1 TLE2 ZNF41
Entrez ID		7592	30012
HPRD ID		02447	06868
Ensembl ID		ENSG00000147124	ENSG00000164438
Uniprot IDs		P51814	O43711
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Fate Commitment Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Primary MiRNA Processing Positive Regulation Of Mesoderm Development Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway SMAD Protein Complex Assembly Negative Regulation Of Cell Differentiation Paraxial Mesoderm Morphogenesis Regulation Of Respiratory Gaseous Exchange By Neurological System Process Nodal Signaling Pathway Regulation Of Cell Development Regulation Of Respiratory System Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis Foregut Morphogenesis Regulation Of Activin Receptor Signaling Pathway Paraxial Mesoderm Development Response To Cholesterol Regulation Of Respiratory Gaseous Exchange Dorsal/ventral Axis Specification Pericardium Development Positive Regulation Of Epithelial To Mesenchymal Transition Activin Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Neuron Fate Specification Gene Silencing By MiRNA Cellular Response To DsRNA Positive Regulation Of BMP Signaling Pathway Insulin Secretion Posttranscriptional Gene Silencing Positive Regulation Of Stem Cell Differentiation Endoderm Formation Embryonic Axis Specification SMAD Protein Signal Transduction Regulation Of Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Respiratory Gaseous Exchange Embryonic Cranial Skeleton Morphogenesis Gene Silencing By RNA Peptide Hormone Secretion Peptide Secretion Digestive Tract Morphogenesis Somatic Stem Cell Maintenance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To DsRNA Neuron Fate Commitment	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Megakaryocyte Differentiation Definitive Hemopoiesis Trophectodermal Cell Differentiation Regulation Of Cellular Process Cellular Metabolic Process Blastocyst Formation Sequestering Of Nodal From Receptor Via Nodal Binding Regulation Of Vasoconstriction By Circulating Norepinephrine Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Nodal Signaling Pathway Negative Regulation Of Myeloid Cell Differentiation Blastocyst Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Peptidyl-cysteine S-nitrosylation Camera-type Eye Morphogenesis Organ Morphogenesis Notch Signaling Pathway Determination Of Left/right Asymmetry In Lateral Mesoderm Positive Regulation Of Skeletal Muscle Tissue Regeneration Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nodal Signaling Pathway Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Sequestering Of Extracellular Ligand From Receptor Eye Morphogenesis Transcription Initiation From RNA Polymerase II Promoter Regulation Of Heart Contraction
Tagcloud ?			abt alls asparaginase attractive bcl bh3 challenge chemotherapeutic correspondence decreases dexamethasone doxorubicin driven exploited gradually highlights hoxa immature intensified loucy lymphoblastic mimetic mostly precursors refractory shows subtypes synergistic tal1
Tagcloud (Difference) ?			abt alls asparaginase attractive bcl bh3 challenge chemotherapeutic correspondence decreases dexamethasone doxorubicin driven exploited gradually highlights hoxa immature intensified loucy lymphoblastic mimetic mostly precursors refractory shows subtypes synergistic tal1
Tagcloud (Intersection) ?