TLX3 and HOPX

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		TLX3	HOPX
Gene Name		T-cell leukemia homeobox 3	HOP homeobox
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding Sequence-specific DNA Binding	DNA Binding
	Biological Process	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Neurological System Process Regulation Of Transcription, DNA-templated Central Nervous System Development Respiratory Gaseous Exchange Negative Regulation Of Neuron Differentiation Neuron Fate Specification	Negative Regulation Of Transcription From RNA Polymerase II Promoter Trophectodermal Cell Differentiation Transcription, DNA-templated Heart Development Regulation Of Heart Contraction Histone Deacetylation Regulation Of Protein Binding Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Cell Differentiation Lung Alveolus Development Positive Regulation Of Striated Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: DENND4A GTF2A1L HIST1H2BJ HNRNPUL1 HOPX ING4 IRF9 LMO2 MEIS1 PPP1CC PQBP1 SNTA1 SP1 TLE1 TLE2 ZNF41	7 interactors: EPC1 HDAC2 HOXB9 SRF TCF12 TLX3 ZSCAN1
Entrez ID		30012	84525
HPRD ID		06868	06280
Ensembl ID		ENSG00000164438	ENSG00000171476
Uniprot IDs		O43711	Q9BPY8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Megakaryocyte Differentiation Definitive Hemopoiesis Trophectodermal Cell Differentiation Regulation Of Cellular Process Cellular Metabolic Process Blastocyst Formation Sequestering Of Nodal From Receptor Via Nodal Binding Regulation Of Vasoconstriction By Circulating Norepinephrine Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Nodal Signaling Pathway Negative Regulation Of Myeloid Cell Differentiation Blastocyst Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Peptidyl-cysteine S-nitrosylation Camera-type Eye Morphogenesis Organ Morphogenesis Notch Signaling Pathway Determination Of Left/right Asymmetry In Lateral Mesoderm Positive Regulation Of Skeletal Muscle Tissue Regeneration Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nodal Signaling Pathway Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Sequestering Of Extracellular Ligand From Receptor Eye Morphogenesis Transcription Initiation From RNA Polymerase II Promoter Regulation Of Heart Contraction See more	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Eyelid Development In Camera-type Eye Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Neurogenesis Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Regulation Of Cell Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cardiac Muscle Cell Development Positive Regulation Of Neurogenesis Hippocampus Development Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Metabolic Process Contractile Actin Filament Bundle Assembly Positive Regulation Of Cell Development Nucleobase-containing Compound Metabolic Process Muscle Structure Development Limbic System Development Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cardiac Muscle Cell Differentiation Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Growth Generation Of Neurons Regulation Of Cell Differentiation Cardiocyte Differentiation Neurogenesis Regulation Of Muscle Cell Differentiation Striated Muscle Cell Development Maintenance Of Chromatin Silencing Negative Regulation Of Beta-amyloid Clearance Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Muscle Cell Development See more
Tagcloud ?		abt alls asparaginase attractive bcl bh3 challenge chemotherapeutic correspondence decreases dexamethasone doxorubicin driven exploited gradually highlights hoxa immature intensified loucy lymphoblastic mimetic mostly precursors refractory shows subtypes synergistic tal1	absorptive anhydrase brdu bromodeoxyuridine caii carbonic cga chromogranin crypts enterocytes enteroendocrine epcam gastrin goblet iesc isomaltase mcm2 minichromosome muc2 mucin obstacle ph3 porcine reserve sim somatostatin sox9 sucrase villin
Tagcloud (Difference) ?		abt alls asparaginase attractive bcl bh3 challenge chemotherapeutic correspondence decreases dexamethasone doxorubicin driven exploited gradually highlights hoxa immature intensified loucy lymphoblastic mimetic mostly precursors refractory shows subtypes synergistic tal1	absorptive anhydrase brdu bromodeoxyuridine caii carbonic cga chromogranin crypts enterocytes enteroendocrine epcam gastrin goblet iesc isomaltase mcm2 minichromosome muc2 mucin obstacle ph3 porcine reserve sim somatostatin sox9 sucrase villin
Tagcloud (Intersection) ?