TLX3 and TEKT5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TLX3	TEKT5
Description		T cell leukemia homeobox 3	tektin 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Cytoplasm Cytoskeleton Cilium Microtubule Cytoskeleton Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Respiratory Gaseous Exchange By Respiratory System Neuron Differentiation Negative Regulation Of Neuron Differentiation Animal Organ Development Neuron Fate Specification GABAergic Neuron Differentiation	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility
Pathways
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Body size at age 10 ( 32376654)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic obstructive pulmonary disease ( 30804561) Eating disorders ( 23568457) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 26635082 30804560) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Nickel levels ( 26025379) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Peak expiratory flow ( 30804560) Resting heart rate ( 27798624)
Interacting Genes		108 interacting genes: ACTMAP ACY1 AKAP9 ANKRD10 ANKRD33 AOC1 APBB1IP ARMC5 ASB12 ATP6V0D1 B9D2 BPIFA1 C2orf42 CEACAM6 CFAP68 CIMIP2B CRX CSNK2B CTNNA3 DENND4A EFEMP2 ERAS FAM168B FCSK FNTB FOSB FOXH1 GGTLC2 GOLGA6L9 GTF2A1L H2BC11 HNF1B HNRNPUL1 HOPX HSPB2 HSPB2-C11orf52 HYI IGFL2 ING4 INTS11 IRF9 ITIH6 KCNJ5-AS1 KRT34 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP19-7 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LMO2 MAGED1 MEIS1 METTL27 MORN5 MSX2 NDUFAB1 NFIC NFIX NHLRC4 NICN1 OIP5 PLA2G10 PLAAT1 POU2AF1 POU6F2 PPP1CC PQBP1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB11 REL ROR2 RSKR SERPINE1 SLC15A2 SMU1 SNTA1 SP1 SPATA46 SPMIP9 SPRYD7 STH SYNGAP1 TBX22 TCIRG1 TEKT5 THTPA TLE2 TMEM42 TOX2 TP53BP1 TRIM42 UFSP1 WDR83 YPEL3 ZBTB32 ZNF34 ZNF41 ZNF44	47 interacting genes: ACTMAP AKAP8L BAG4 CABP2 CSKMT DTX2 EPHB6 EYA2 FNDC3B FOXH1 FOXI1 GSK3B HGS HOXA1 HOXB6 KLHL38 KRTAP12-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP6-2 LASP1 MAPKBP1 MGAT5B NFKBID NHLRC2 PITX1 PLSCR4 PROP1 PSMB4 QRICH1 RBPMS RORB RUNX1 SMARCB1 SMUG1 SPAG8 SPMIP4 SSC4D TBX15 TLX3 TNS2 TOX2 USP54 VENTX ZMYND12 ZNF76
Entrez ID		30012	146279
HPRD ID		06868	08736
Ensembl ID		ENSG00000164438	ENSG00000153060
Uniprot IDs		O43711	Q96M29
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Chromatin	Positive Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Chromatin Positive Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Hepatocyte Differentiation
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