XPNPEP1 and RINT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		XPNPEP1	RINT1
Description		X-prolyl aminopeptidase 1	RAD50 interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Dsl1/NZR Complex
	Molecular Function	Aminopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Manganese Ion Binding Protein Homodimerization Activity Metal Ion Binding Metalloaminopeptidase Activity	Protein Binding
	Biological Process	Proteolysis Bradykinin Catabolic Process Negative Regulation Of Programmed Cell Death CARD8 Inflammasome Complex Assembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Mitotic G2 DNA Damage Checkpoint Signaling Protein Transport Vesicle-mediated Transport Regulation Of ER To Golgi Vesicle-mediated Transport
Pathways			COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Biliary atresia ( 20460270) Bipolar disorder ( 28072414 31043756) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: DISC1 GORASP2 GSK3B HBG2 MAPK9 NUDT3 POLA2 RHOH RINT1 SUMO2 UBC UBE2D3	101 interacting genes: AIRIM ANKRD11 ARHGAP45 ARNT2 BFSP2 BLOC1S6 BNIP3L C19orf44 C1orf35 CCDC120 CCDC121 CCDC146 CCDC187 CCDC57 CCDC88B CCHCR1 CDR2L CEP57L1 CSPP1 CWF19L2 DCTN2 DCX DPF2 DRC4 EPC1 ESRRG EXOC8 FAM107A FAM110A FAM124B FAM161A FAM161B FAM81B FAM90A1 FANCG FCHSD2 GFI1B GRAP2 HDAC4 HGS INPP5J JMY KIAA1217 KRT1 LMO2 LSP1P3 LYSMD1 MBD3 MCM7 MISP MYOZ3 NAB2 NFIL3 PCM1 PIK3R2 PIMREG PRPF18 PRPF31 PSTPIP1 RAD50 RAMAC RB1 RBL1 RBL2 RBM41 RIBC1 RNF39 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN SUOX TACO1 TEX9 TRIM69 TSEN54 TSHZ2 TSHZ3 TXLNA USHBP1 UTP14C VAV3 VPS37C XPNPEP1 ZBTB16 ZC2HC1C ZNF648 ZNF655 ZNF688 ZNF697 ZNF835 ZSCAN5B ZW10
Entrez ID		7511	60561
HPRD ID		03899	15250
Ensembl ID		ENSG00000108039	ENSG00000135249
Uniprot IDs		Q5T6H7 Q9NQW7	Q6NUQ1
PDB IDs		3CTZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Tag Activity Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Cell Adhesion Presynapse Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Microtubule Anchoring At Centrosome Glutamatergic Synapse Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane Cytosol Positive Regulation Of Cell-matrix Adhesion Superior Temporal Gyrus Development Ubiquitin Protein Ligase Binding Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Protein Localization To Tricellular Tight Junction 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol Phosphate Catabolic Process Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Positive Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Establishment Of Protein Localization TOR Signaling Regulation Of Axon Extension JUN Kinase Activity Diphosphoinositol Polyphosphate Metabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Pyramidal Neuron Migration To Cerebral Cortex Central Region Of Growth Cone	Protein Binding Cytoskeleton Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition Microtubule Cytoskeleton Organization Microtubule-based Process Centrosome SWI/SNF Complex Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition NBAF Complex Nuclear Speck Negative Regulation Of Cell Cycle Process Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Double-strand Break Repair Microtubule Anchoring Centriole Protein Localization To Centrosome Regulation Of Sister Chromatid Segregation Cytoskeleton Organization Nucleoplasm Regulation Of Nucleotide-excision Repair Microtubule Binding
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