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XPNPEP1
Gene Name
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Aminopeptidase Activity
Manganese Ion Binding
Protein Homodimerization Activity
Metalloaminopeptidase Activity
Biological Process
Proteolysis
Bradykinin Catabolic Process
Pathways
Drugs
Diseases
GWAS
Biliary atresia (
20460270
)
Protein-protein Interactions
8 interactors:
DISC1
GSK3B
MAPK9
NUDT3
POLA2
RINT1
UBC
UBE2D3
Entrez ID
7511
HPRD ID
03899
Ensembl ID
ENSG00000108039
Uniprot IDs
G8JLB2
Q9NQW7
PDB IDs
3CTZ
Enriched GO Terms of Interacting Partners
?
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Proteolysis
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Wnt Signaling Pathway
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Innate Immune Response
Cellular Localization
Response To Growth Factor
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Protein Ubiquitination
Regulation Of Proteolysis
Positive Regulation Of Protein Catabolic Process
Fc-epsilon Receptor Signaling Pathway
Intracellular Transport
Regulation Of Innate Immune Response
Fc Receptor Signaling Pathway
Innate Immune Response
Negative Regulation Of Type I Interferon Production
Regulation Of Wnt Signaling Pathway
Regulation Of Immune Response
Positive Regulation Of Protein Modification Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Regulation Of DNA-templated Transcription In Response To Stress
Protein Localization
Apoptotic Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Apoptotic Process
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Glycogen Metabolic Process
Establishment Of Localization In Cell
Programmed Cell Death
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Catabolic Process
Cell Death
Death
MyD88-dependent Toll-like Receptor Signaling Pathway
Response To Abiotic Stimulus
Tagcloud
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aminopeptidase
app
app1
apps
associate
biologically
causal
cleave
cytosolic
deficiency
deficient
excretion
imino
isoforms
knocking
lethality
link
mammals
microcephaly
modest
oligopeptide
penultimate
peptides
peptiduria
proline
ps
residue
retardation