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XBP1 and PCBD2
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
XBP1
PCBD2
Gene Name
X-box binding protein 1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Integral Component Of Endoplasmic Reticulum Membrane
Cellular_component
Nucleus
Mitochondrion
Molecular Function
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Core Promoter Binding
RNA Polymerase II Transcription Factor Binding
Enhancer Sequence-specific DNA Binding
Protease Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Protein Kinase Binding
Chromatin DNA Binding
Ubiquitin Protein Ligase Binding
Transcription Regulatory Region DNA Binding
Protein Heterodimerization Activity
Phenylalanine 4-monooxygenase Activity
Protein Binding
4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Angiogenesis
Liver Development
Positive Regulation Of Protein Phosphorylation
Endothelial Cell Proliferation
Positive Regulation Of Immunoglobulin Production
Transcription From RNA Polymerase II Promoter
Ubiquitin-dependent Protein Catabolic Process
Immune Response
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Positive Regulation Of Autophagy
Negative Regulation Of Myotube Differentiation
Phosphatidylinositol 3-kinase Signaling
Cell Growth
Endoplasmic Reticulum Unfolded Protein Response
Exocrine Pancreas Development
Positive Regulation Of Histone Methylation
Regulation Of Protein Stability
Protein Destabilization
Cellular Response To Nutrient
Positive Regulation Of TOR Signaling
Cellular Response To Insulin Stimulus
Cellular Response To Oxidative Stress
Response To Endoplasmic Reticulum Stress
Cellular Triglyceride Homeostasis
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cellular Response To Glucose Starvation
Response To Drug
Cholesterol Homeostasis
Positive Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Apoptotic Process
Cellular Protein Metabolic Process
Positive Regulation Of MHC Class II Biosynthetic Process
Positive Regulation Of B Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neuron Development
Positive Regulation Of Immunoglobulin Secretion
Response To Electrical Stimulus
Fatty Acid Homeostasis
Sterol Homeostasis
Serotonin Secretion, Neurotransmission
Adipose Tissue Development
Epithelial Cell Maturation Involved In Salivary Gland Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Antibiotic
Cellular Response To Fructose Stimulus
Cellular Response To Glucose Stimulus
Cellular Response To Interleukin-4
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Fluid Shear Stress
Cellular Response To Laminar Fluid Shear Stress
Positive Regulation Of Plasma Cell Differentiation
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Acetylation
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Lactation
Response To Insulin-like Growth Factor Stimulus
Positive Regulation Of Hepatocyte Proliferation
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Interleukin-6 Secretion
Tetrahydrobiopterin Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Protein Homotetramerization
Protein Heterooligomerization
Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Esophageal cancer (squamous cell) (
22960999
)
Bulimia nervosa (
23568457
)
Colorectal cancer (
23263487
)
Height (
18391951
)
Protein-Protein Interactions
19 interactors:
ATF6
ATF6B
CREBZF
ESR1
FOS
FUBP3
GLI1
H1F0
H1FX
HDGF
NR0B2
PCBD2
RBL2
SRSF1
SSX4
TRIP4
UBE2I
ZNF440
ZNF580
31 interactors:
AATF
APP
ASCC2
BRF1
C1D
CDC5L
CENPK
CHAF1A
GTF2E1
HES4
IRF2BP1
KCNIP3
MAGEA11
MED21
MED30
MED4
MED7
MET
PBXIP1
PCBD1
PHF14
PML
RUNX1T1
SNW1
SSX3
SSX5
STAT3
TAL2
TGIF2LY
XBP1
ZZZ3
Entrez ID
7494
84105
HPRD ID
01908
17824
Ensembl ID
ENSG00000100219
Uniprot IDs
P17861
Q9H0N5
PDB IDs
4C45
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Biosynthetic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Cellular Response To Topologically Incorrect Protein
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Estrogen Receptor Signaling Pathway
Response To Unfolded Protein
Response To Endoplasmic Reticulum Stress
Regulation Of Cellular Process
Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Positive Regulation Of SUMO Transferase Activity
Positive Regulation Of Nuclease Activity
Regulation Of DNA-templated Transcription In Response To Stress
Intracellular Steroid Hormone Receptor Signaling Pathway
Chromatin Organization
Cellular Response To Organic Substance
Notochord Regression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Positive Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Apoptotic Process
Negative Regulation Of Gene Expression
Programmed Cell Death
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Cell Death
Death
Stem Cell Maintenance
Transcription From RNA Polymerase II Promoter
Cell Differentiation
Positive Regulation Of Histone Modification
Negative Regulation Of Cell Differentiation
Stem Cell Development
Developmental Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Differentiation
Tagcloud
?
alter
apc
apoptotic
bcl2
challenged
chop
contributing
cytoprotective
decreasing
dr5
enterohemorrhagic
fold
hemolytic
hsp40
kidneys
later
producing
ribotoxic
rodentium
saline
shiga
spliced
stx
stx2
toxigenic
toxins
transcripts
untreated
uremic
Tagcloud (Difference)
?
alter
apc
apoptotic
bcl2
challenged
chop
contributing
cytoprotective
decreasing
dr5
enterohemorrhagic
fold
hemolytic
hsp40
kidneys
later
producing
ribotoxic
rodentium
saline
shiga
spliced
stx
stx2
toxigenic
toxins
transcripts
untreated
uremic
Tagcloud (Intersection)
?