VBP1 and TSC22D4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VBP1	TSC22D4
Description		VHL binding protein 1	TSC22 domain family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Prefoldin Complex Protein-containing Complex	Nucleus Cytoplasm Dendrite Cell Projection Synapse
	Molecular Function	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Glucose Homeostasis Negative Regulation Of DNA-templated Transcription Neuron Cellular Homeostasis Neuron Projection Extension
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Platelet count ( 27863252) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		31 interacting genes: AIRIM DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 HIF1A IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBC UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576	61 interacting genes: ABLIM1 AIFM1 ARHGAP9 BLZF1 CBX8 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU CTNNAL1 ENKD1 FBXW7 FRMD6 FXR2 GOLGA2 GORASP2 KPNA2 KRT40 LBP LMO1 LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP MYO15B NIF3L1 NOC4L NRBP1 PCBP1 PCDH17 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 RACK1 SACS SAT1 SMAD3 SMARCB1 SYT17 TEX11 TLE5 TRIM55 TRIM63 TSC22D1 TSPOAP1 UBLCP1 VBP1 ZBTB24 ZMYND10 ZNF580
Entrez ID		7411	81628
HPRD ID		02135	18231
Ensembl ID		ENSG00000155959	ENSG00000166925
Uniprot IDs		P61758 Q6FH24	B4DKI8 Q9Y3Q8
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Phosphate Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT	Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Protein Binding Organelle Organization Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Cytoplasm Negative Regulation Of Protein Metabolic Process Regulation Of Protein Stability Negative Regulation Of Amyloid-beta Formation Cellular Response To Glucose Stimulus Phosphothreonine Residue Binding Cellular Response To Hydrogen Peroxide Protein Localization To Lipid Droplet Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Glucose Mediated Signaling Pathway Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Carbohydrate Stimulus Organelle Disassembly Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Regulation Of Amide Metabolic Process Protein Stabilization Regulation Of Protein Metabolic Process Viral RNA Genome Replication Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Intracellular Glucose Homeostasis Protein Ubiquitination Identical Protein Binding Regulation Of Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Catabolic Process Regulation Of Protein Modification Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Response To Hydrogen Peroxide Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Ubiquitin-protein Transferase Activator Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Release Of Cytochrome C From Mitochondria
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