TSC22D4 and NRBP1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		TSC22D4	NRBP1
Gene Name		TSC22 domain family, member 4	nuclear receptor binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Response To Osmotic Stress Negative Regulation Of Transcription, DNA-templated	Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation ER To Golgi Vesicle-mediated Transport Gene Expression
Pathways			Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		53 interactors: ABLIM1 AES AIFM1 APIP BLZF1 BZRAP1 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU ENKD1 FRMD6 FXR2 GNB2L1 GOLGA2 GORASP2 KEAP1 KPNA2 KRT40 LBP LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP NIF3L1 NOC4L NRBP1 NRBP2 PCBP1 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 SACS SAT1 SMAD3 SYT17 TEX11 TSC22D1 UBLCP1 ZBTB24 ZMYND10 ZNF580	11 interactors: CDKN1A CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 TK1 TSC22D4
Entrez ID		81628	29959
HPRD ID		18231	05819
Ensembl ID		ENSG00000166925	ENSG00000115216
Uniprot IDs		A8MWR6 Q9Y3Q8	Q9UHY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Cell Cycle Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Proteolysis Negative Regulation Of Cell Cycle Positive Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Cellular Process Cell Cycle Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cytokine Production Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Ubiquitination Negative Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of Protein Phosphorylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Signal Transduction Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Negative Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Glycolytic Process Cellular Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Cell Cycle Cell Cycle Arrest Response To External Stimulus Response To Abiotic Stimulus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Tube Development Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Response To Organic Substance Regulation Of Kinase Activity Cellular Metabolic Process Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Cellular Response To Ionizing Radiation Glycogen Metabolic Process Positive Regulation Of Phosphorylation Cellular Response To Heat Positive Regulation Of Protein Modification Process Cellular Response To Mechanical Stimulus Response To Hormone Fetal Process Involved In Parturition Negative Regulation Of Phosphorylation Polysaccharide Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Cycle Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Phosphorylation Signal Transduction In Response To DNA Damage Response To Radiation Negative Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Skeletal Muscle Cell Proliferation Superior Temporal Gyrus Development Heterocycle Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Aromatic Compound Metabolic Process Response To Heat Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Regulation Of Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Phosphatidylinositol-mediated Signaling Energy Reserve Metabolic Process Digestive Tract Development
Tagcloud ?		ablation cachectic cachexia clone deprivation diminished hepatic hepatocytes hypertriglyceridemia hypo hypobetalipoproteinemia lipids lipogenic livers mammals metabolic mimicking output proper rationale rescued secretion storage transforming triggers vldl wasting
Tagcloud (Difference) ?		ablation cachectic cachexia clone deprivation diminished hepatic hepatocytes hypertriglyceridemia hypo hypobetalipoproteinemia lipids lipogenic livers mammals metabolic mimicking output proper rationale rescued secretion storage transforming triggers vldl wasting
Tagcloud (Intersection) ?