VBP1 and GPANK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VBP1	GPANK1
Description		VHL binding protein 1	G-patch domain and ankyrin repeats 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Prefoldin Complex Protein-containing Complex
	Molecular Function	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Febrile seizures (MMR vaccine-related) ( 25344690) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		31 interacting genes: AIRIM DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 HIF1A IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBC UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576	90 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CIMIP2B CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FTO GOLGA2 GOLGA6L9 GPRASP3 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 VHL ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1
Entrez ID		7411	7918
HPRD ID		02135	00810
Ensembl ID		ENSG00000155959	ENSG00000204438
Uniprot IDs		P61758 Q6FH24	A0A024RCU2 A0A0G2JHL1 A0A1U9X7R4 B2RA66 O95872
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Phosphate Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT	Protein Binding Nucleus Regulation Of Supramolecular Fiber Organization Asymmetric Cell Division
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