VPS51 and VPS52

Number of citations of the paper that reports this interaction (PMID 20685960)
14

Data Source:
BioGRID (two hybrid, pull down, biochemical)

		VPS51	VPS52
Gene Name		vacuolar protein sorting 51 homolog (S. cerevisiae)	vacuolar protein sorting 52 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	GARP Complex Golgi Apparatus Integral Component Of Membrane	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Protein Binding Syntaxin Binding
	Biological Process	Lipid Transport Autophagy Protein Transport Retrograde Transport, Endosome To Golgi	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CDKN1A GSK3B NUDT3 VPS52 VPS53 VPS54 YTHDC1	49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2
Entrez ID		738	6293
HPRD ID		12605	09142
Ensembl ID		ENSG00000149823	ENSG00000223501
Uniprot IDs		Q9UID3	B4DNI9 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Heat Retrograde Transport, Endosome To Golgi Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Protein Transport Establishment Of Protein Localization Response To Heat Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Protein Serine/threonine Kinase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Digestive System Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Protein Import Into Nucleus Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Protein Localization Cellular Response To Fibroblast Growth Factor Stimulus Response To Temperature Stimulus Response To Fibroblast Growth Factor Cellular Response To Interleukin-3 Intestinal Epithelial Cell Maturation Regulation Of Protein Localization To Nucleus Endosomal Transport Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Ectodermal Cell Differentiation Negative Regulation Of Protein Kinase Activity Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Kinase Activity Cellular Response To UV-B Golgi To Vacuole Transport Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Regulation Of Intracellular Protein Transport Fc Receptor Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Stress-induced Premature Senescence	Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Difference) ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Intersection) ?