VPS51 and VPS53

Number of citations of the paper that reports this interaction (PMID 20685960)
14

Data Source:
BioGRID (two hybrid, pull down, biochemical)

		VPS51	VPS53
Gene Name		vacuolar protein sorting 51 homolog (S. cerevisiae)	vacuolar protein sorting 53 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	GARP Complex Golgi Apparatus Integral Component Of Membrane	GARP Complex Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Lipid Transport Autophagy Protein Transport Retrograde Transport, Endosome To Golgi	Protein Transport Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		7 interactors: CDKN1A GSK3B NUDT3 VPS52 VPS53 VPS54 YTHDC1	4 interactors: EXOC2 VPS51 VPS52 VPS54
Entrez ID		738	55275
HPRD ID		12605	07720
Ensembl ID		ENSG00000149823	ENSG00000141252
Uniprot IDs		Q9UID3	B3KS06 Q5VIR6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Heat Retrograde Transport, Endosome To Golgi Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Protein Transport Establishment Of Protein Localization Response To Heat Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Protein Serine/threonine Kinase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Digestive System Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Protein Import Into Nucleus Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Protein Localization Cellular Response To Fibroblast Growth Factor Stimulus Response To Temperature Stimulus Response To Fibroblast Growth Factor Cellular Response To Interleukin-3 Intestinal Epithelial Cell Maturation Regulation Of Protein Localization To Nucleus Endosomal Transport Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Ectodermal Cell Differentiation Negative Regulation Of Protein Kinase Activity Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Kinase Activity Cellular Response To UV-B Golgi To Vacuole Transport Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Regulation Of Intracellular Protein Transport Fc Receptor Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Stress-induced Premature Senescence	Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Golgi To Plasma Membrane Transport Protein Transport Establishment Of Protein Localization Protein Localization Retrograde Transport, Endosome To Golgi Cytoplasmic Transport Embryonic Ectodermal Digestive Tract Development Endosomal Transport Vesicle-mediated Transport Ectodermal Cell Differentiation Intracellular Transport Golgi To Vacuole Transport Transport Establishment Of Localization In Cell Neurofilament Cytoskeleton Organization Cellular Localization Ectoderm Development Homeostasis Of Number Of Cells Within A Tissue Intermediate Filament Cytoskeleton Organization Embryonic Digestive Tract Development Intermediate Filament-based Process Musculoskeletal Movement Vacuolar Transport Digestive Tract Development Digestive System Development
Tagcloud ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler
Tagcloud (Difference) ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler
Tagcloud (Intersection) ?