SCGB1A1 and TRIM32

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SCGB1A1	TRIM32
Gene Name		secretoglobin, family 1A, member 1 (uteroglobin)	tripartite motif containing 32
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nuclear Envelope Rough Endoplasmic Reticulum Secretory Granule Extracellular Vesicular Exosome	Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament
	Molecular Function	Protein Binding Phospholipase A2 Inhibitor Activity	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Female Pregnancy Embryo Implantation Response To Xenobiotic Stimulus Response To Ozone Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-4 Production Negative Regulation Of Interleukin-5 Production Response To Silicon Dioxide Response To Cytokine Negative Regulation Of T Cell Proliferation Response To Drug Negative Regulation Of Catalytic Activity Regulation Of MRNA Stability Regulation Of Inflammatory Response Response To Glucocorticoid Response To Fibroblast Growth Factor	Protein Polyubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Motility
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Regulation of innate immune responses to cytosolic DNA Cytosolic sensors of pathogen-associated DNA Class I MHC mediated antigen processing & presentation Innate Immune System Adaptive Immune System
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
Protein-Protein Interactions		5 interactors: CUBN FN1 LMBR1L LRP2 TRIM32	36 interactors: ABI2 ATXN1 CLIP4 DTNBP1 GLIS2 IRAK1 KCTD9 MID2 MYCN PDE9A PIAS3 PIAS4 PTCD2 PTPN11 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP SYT6 TMEM173 TOP1 TRIM23 TRIM27 TRIM5 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2U UBQLN1 UBQLN4 VPS11 XIAP
Entrez ID		7356	22954
HPRD ID		01884	03797
Ensembl ID		ENSG00000149021	ENSG00000119401
Uniprot IDs		P11684	Q13049
PDB IDs			2CT2
Enriched GO Terms of Interacting Partners?		Vitamin D Metabolic Process Vesicle-mediated Transport Endocytosis Vitamin Metabolic Process Positive Regulation Of Cell Growth Calcium-independent Cell-matrix Adhesion Positive Regulation Of Growth Steroid Metabolic Process Cobalamin Transport Positive Regulation Of Proteolysis Positive Regulation Of Neuron Differentiation Response To Light Stimulus Alcohol Metabolic Process Regulation Of Cell Growth Receptor-mediated Endocytosis Integrin Activation Positive Regulation Of Neurogenesis Negative Regulation Of Viral Release From Host Cell Response To Radiation Cobalamin Metabolic Process Lipoprotein Transport Positive Regulation Of Cell Development Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Neuron Differentiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Protein K48-linked Ubiquitination Regulation Of Innate Immune Response Cellular Protein Modification Process Activation Of Innate Immune Response Protein K63-linked Ubiquitination Positive Regulation Of Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Metabolic Process Cellular Response To Oxygen Levels Cellular Protein Metabolic Process Regulation Of Immune System Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response Innate Immune Response-activating Signal Transduction Negative Regulation Of Viral Release From Host Cell TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Stimulus Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Response To Stress Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Regulation Of Gene Expression Proteasomal Protein Catabolic Process Protein Metabolic Process ISG15-protein Conjugation Immune Response-regulating Signaling Pathway Immune Response Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Defense Response Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Stimulus Cellular Protein Catabolic Process Regulation Of RNA Metabolic Process
Tagcloud ?		bmp4 branching catenin cc10 coactivator determination disrupted distal embryonic epicardial epithelium ex fgf10 genetically hallmarks histology iq1 lung lungs morphogenesis pharmacologically proximal proximalized proximalizes reinitiated reversible sox2 usage utero	arrest binds e3 element ensure impairing interacts largely ligase maintaining modifications negatively oncogenic overexpressed p53 preventing promotes proper regulator responsive senescence stress tightly transcriptionally translational tumorigenesis turn ubiquitin ubiquitination
Tagcloud (Difference) ?		bmp4 branching catenin cc10 coactivator determination disrupted distal embryonic epicardial epithelium ex fgf10 genetically hallmarks histology iq1 lung lungs morphogenesis pharmacologically proximal proximalized proximalizes reinitiated reversible sox2 usage utero	arrest binds e3 element ensure impairing interacts largely ligase maintaining modifications negatively oncogenic overexpressed p53 preventing promotes proper regulator responsive senescence stress tightly transcriptionally translational tumorigenesis turn ubiquitin ubiquitination
Tagcloud (Intersection) ?