SCGB1A1 and TMEM43

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCGB1A1	TMEM43
Description		secretoglobin family 1A member 1	transmembrane protein 43
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nuclear Envelope Cytoplasm Secretory Granule Extracellular Exosome	Nucleus Nuclear Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Protein Binding Phospholipase A2 Inhibitor Activity Polychlorinated Biphenyl Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Female Pregnancy Embryo Implantation Response To Xenobiotic Stimulus Response To Ozone Response To Lipopolysaccharide Negative Regulation Of Type II Interferon Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-4 Production Negative Regulation Of Interleukin-5 Production Response To Silicon Dioxide Response To Cytokine T Cell Proliferation Negative Regulation Of T Cell Proliferation Regulation Of MRNA Stability Regulation Of Inflammatory Response Response To Glucocorticoid Response To Fibroblast Growth Factor	Immune System Process Lipid Metabolic Process Innate Immune Response Nuclear Membrane Organization
Pathways
Drugs		4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Gamma glutamyl transferase levels ( 29403010) Serum CC16 levels ( 32839289) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Heel bone mineral density ( 30598549) Longevity ( 33657282)
Interacting Genes		7 interacting genes: AQP6 CUBN FN1 LMBR1L LRP2 TMEM43 TRIM32	16 interacting genes: APOA5 ARL13B CARD10 CISD2 FAM209A FDFT1 FGA FKBP8 GRAMD2B LMNA PCYT1B SCGB1A1 SIAH1 SYNDIG1 USP25 ZCCHC12
Entrez ID		7356	79188
HPRD ID		01884	15541
Ensembl ID		ENSG00000149021	ENSG00000170876
Uniprot IDs		A0A0S2Z4R6 P11684	A0A024R2F9 Q9BTV4
PDB IDs		7VF3 7VG7
Enriched GO Terms of Interacting Partners?		Cobalamin Transport Cargo Receptor Activity Receptor-mediated Endocytosis Nitrate Transmembrane Transporter Activity Axon Development Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Endoplasmic Reticulum Brush Border Membrane Brush Border Alcohol Metabolic Process Vitamin Transport Steroid Metabolic Process Positive Regulation Of Interleukin-17-mediated Signaling Pathway Actin Ubiquitination Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Clathrin-coated Pit Endocytic Vesicle PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Apical Plasma Membrane Regulation Of Fibroblast Proliferation Regulation Of Neurogenesis Folate Import Across Plasma Membrane Positive Regulation Of Oligodendrocyte Progenitor Proliferation Lysosomal Membrane Apical Part Of Cell Extrinsic Component Of External Side Of Plasma Membrane Vesicle Tethering To Endoplasmic Reticulum Protein Localization To Phagocytic Vesicle Positive Regulation Of Cell Development Regulation Of Nervous System Development Endocytosis Negative Regulation Of Monocyte Activation Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Lipid Metabolic Process Folate Transmembrane Transport Cholesterol Metabolic Process Striated Muscle Myosin Thick Filament Sterol Metabolic Process Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Calcium-independent Cell-matrix Adhesion Endoplasmic Reticulum-endosome Membrane Contact Site Actin Modification Regulation Of Cell Shape Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Microtubule Bundle Regulation Of Axonogenesis Positive Regulation Of Lysosomal Protein Catabolic Process
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