TRIM32 and SYT6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM32	SYT6
Gene Name		tripartite motif containing 32	synaptotagmin VI
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament	Cytosol Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Cell Junction Synaptic Vesicle Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity	Transporter Activity Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Protein Polyubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Motility	Acrosomal Vesicle Exocytosis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Regulation of innate immune responses to cytosolic DNA Cytosolic sensors of pathogen-associated DNA Class I MHC mediated antigen processing & presentation Innate Immune System Adaptive Immune System
Drugs
Diseases
GWAS			Breast cancer (prognosis) ( 23319801) Obesity-related traits ( 23251661)
Protein-Protein Interactions		36 interactors: ABI2 ATXN1 CLIP4 DTNBP1 GLIS2 IRAK1 KCTD9 MID2 MYCN PDE9A PIAS3 PIAS4 PTCD2 PTPN11 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP SYT6 TMEM173 TOP1 TRIM23 TRIM27 TRIM5 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2U UBQLN1 UBQLN4 VPS11 XIAP	15 interactors: APP BRCA1 DVL3 FXR2 GOLGA2 KCTD9 KRT40 MTUS2 NRXN1 PRKCB TNIP1 TRIM32 TSGA10 ZBTB43 ZBTB8A
Entrez ID		22954	148281
HPRD ID		03797	09654
Ensembl ID		ENSG00000119401	ENSG00000134207
Uniprot IDs		Q13049	I6L9C3 Q5T7P8
PDB IDs		2CT2
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Protein K48-linked Ubiquitination Regulation Of Innate Immune Response Cellular Protein Modification Process Activation Of Innate Immune Response Protein K63-linked Ubiquitination Positive Regulation Of Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Metabolic Process Cellular Response To Oxygen Levels Cellular Protein Metabolic Process Regulation Of Immune System Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response Innate Immune Response-activating Signal Transduction Negative Regulation Of Viral Release From Host Cell TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Stimulus Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Response To Stress Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Regulation Of Gene Expression Proteasomal Protein Catabolic Process Protein Metabolic Process ISG15-protein Conjugation Immune Response-regulating Signaling Pathway Immune Response Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Defense Response Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Stimulus Cellular Protein Catabolic Process Regulation Of RNA Metabolic Process	Negative Regulation Of Signal Transduction Regulation Of Gene Expression Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Cell Cycle Regulation Of Signaling Positive Regulation Of Histone H4-K20 Methylation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Viral Process Neuromuscular Process Controlling Balance Synapse Assembly Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Histone H3-T6 Phosphorylation Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Regulation Of Synapse Structure Or Activity Regulation Of Nitrogen Compound Metabolic Process Response To Radiation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Gephyrin Clustering Synaptic Vesicle Clustering Regulation Of Receptor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Angiogenesis Response To Tumor Necrosis Factor Neuronal Signal Transduction Regulation Of Response To DNA Damage Stimulus Response To Abiotic Stimulus Neuromuscular Process Positive Regulation Of Cellular Protein Metabolic Process Learning Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Non-canonical Wnt Signaling Pathway Via JNK Cascade N-methyl-D-aspartate Receptor Clustering Vocal Learning Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Binding
Tagcloud ?		arrest binds e3 element ensure impairing interacts largely ligase maintaining modifications negatively oncogenic overexpressed p53 preventing promotes proper regulator responsive senescence stress tightly transcriptionally translational tumorigenesis turn ubiquitin ubiquitination
Tagcloud (Difference) ?		arrest binds e3 element ensure impairing interacts largely ligase maintaining modifications negatively oncogenic overexpressed p53 preventing promotes proper regulator responsive senescence stress tightly transcriptionally translational tumorigenesis turn ubiquitin ubiquitination
Tagcloud (Intersection) ?