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UBE2E1 and RNF128
Number of citations of the paper that reports this interaction (PubMedID
12705856
)
0
Data Source:
BioGRID
(pull down)
UBE2E1
RNF128
Description
ubiquitin conjugating enzyme E2 E1
ring finger protein 128
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Cytoplasm
Late Endosome
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Cytoskeleton
Endomembrane System
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
ISG15 Transferase Activity
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Negative Regulation Of Gene Expression
Protein Ubiquitination
ISG15-protein Conjugation
Positive Regulation Of Transcription By RNA Polymerase II
Protein K48-linked Ubiquitination
Negative Regulation Of Cytokine Production
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Regulation Of Protein Stability
Protein Localization To Lysosome
Positive Regulation Of Protein Catabolic Process In The Vacuole
Pathways
ISG15 antiviral mechanism
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
Assembly of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Ub-specific processing proteases
Ovarian tumor domain proteases
Drugs
Diseases
GWAS
Academic attainment (English) (
33594131
)
Acne (severe) (
24927181
)
Extremely high intelligence (
29520040
)
Metabolite levels (
23823483
)
Alcoholic chronic pancreatitis (
28754779
)
Creatinine levels (
31015462
)
Estimated glomerular filtration rate (
31015462
)
Interacting Genes
116 interacting genes:
ARIH2
ARK2C
ASXL2
BARD1
BIRC7
BIRC8
BRCA1
CADPS2
CBL
CHFR
CNOT4
CUL3
DTX1
DTX3
DTX3L
DZIP3
EPS15
F12
FBXO2
FBXO7
HDAC6
IPO11
ITCH
JADE1
LRSAM1
MAP3K1
MARCHF2
MARCHF3
MARCHF5
MARCHF7
MDM2
MGRN1
MID1
MKRN3
MUL1
NEDD4
NEDD4L
NHLRC1
PAEP
PBX2
POLL
POLM
PRKN
RBX1
RELA
RFWD3
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF122
RNF128
RNF13
RNF130
RNF14
RNF150
RNF152
RNF166
RNF167
RNF168
RNF169
RNF181
RNF185
RNF2
RNF20
RNF26
RNF31
RNF34
RNF4
RNF43
RNF5
RNF8
STUB1
TOPORS
TRAF6
TRIM13
TRIM17
TRIM2
TRIM21
TRIM23
TRIM27
TRIM28
TRIM29
TRIM3
TRIM32
TRIM33
TRIM37
TRIM38
TRIM39
TRIM45
TRIM50
TRIM69
TRIM7
UBA1
UBA6
UBA7
UBASH3B
UBC
UBE2G1
UBE3A
UBOX5
UBR5
UBR7
UFM1
USP7
UVSSA
WWP2
XIAP
ZNG1E
ZNRF1
ZNRF2
ZNRF4
18 interacting genes:
APPBP2
CD151
CD40LG
CD81
CEP76
EGFR
EPOR
OTUB1
PDCD1
SNX17
TBK1
TP53
UBE2E1
UBE2H
UBE2I
UBE2N
UBE2T
UBQLN2
Entrez ID
7324
79589
HPRD ID
04225
02340
Ensembl ID
ENSG00000170142
ENSG00000133135
Uniprot IDs
B7Z306
P51965
Q8TEB7
PDB IDs
1XR9
3BZH
4JJQ
5LBN
6FGA
8IYA
3ICU
Enriched GO Terms of Interacting Partners
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Ubiquitin Protein Ligase Activity
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Ubiquitin-protein Transferase Activity
Protein Modification Process
Protein Polyubiquitination
Transferase Activity
Protein Metabolic Process
Zinc Ion Binding
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Macromolecule Catabolic Process
Proteolysis
Metal Ion Binding
Macromolecule Metabolic Process
Protein Autoubiquitination
Catabolic Process
Protein K48-linked Ubiquitination
Protein K63-linked Ubiquitination
Proteasomal Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Ubiquitin Ligase Complex
Cellular Response To Stress
Ubiquitin Protein Ligase Binding
Response To Stress
Regulation Of Post-translational Protein Modification
Cytoplasm
Positive Regulation Of Catabolic Process
Ubiquitin Binding
Positive Regulation Of Post-translational Protein Modification
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Autophagy
DNA Damage Response
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Ubiquitination
Protein K6-linked Ubiquitination
Negative Regulation Of Signal Transduction
Innate Immune Response
Regulation Of Signal Transduction
Immune System Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Protein Catabolic Process
Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Ubiquitin Conjugating Enzyme Activity
Proteolysis Involved In Protein Catabolic Process
Catabolic Process
Macromolecule Catabolic Process
Mononuclear Cell Proliferation
Proteasomal Protein Catabolic Process
Positive Regulation Of Intracellular Signal Transduction
Leukocyte Proliferation
Ubiquitin Protein Ligase Binding
Proteolysis
Post-translational Protein Modification
Protein Monoubiquitination
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
TORC1 Signaling
Negative Regulation Of TORC1 Signaling
Protein Modification By Small Protein Conjugation
Positive Regulation Of Canonical NF-kappaB Signal Transduction
TOR Signaling
Positive Regulation Of T Cell Apoptotic Process
Positive Regulation Of Signal Transduction
Negative Regulation Of TOR Signaling
Protein Modification Process
Ubiquitin-protein Transferase Activity
Cellular Response To Nutrient Levels
Regulation Of TORC1 Signaling
Positive Regulation Of Lymphocyte Apoptotic Process
Regulation Of Cellular Response To Stress
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Positive Regulation Of Cell Communication
Lymphocyte Proliferation
Positive Regulation Of Signaling
Protein Metabolic Process
Lymphocyte Activation Involved In Immune Response
Regulation Of Canonical NF-kappaB Signal Transduction
Immune System Process
ATP Binding
Protein Ubiquitination
T Cell Apoptotic Process
Cytosol
Positive Regulation Of Leukocyte Apoptotic Process
Integrin Binding
Regulation Of Intracellular Signal Transduction
Regulation Of TOR Signaling
Leukocyte Activation Involved In Immune Response
Cellular Localization
Cell Activation Involved In Immune Response
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Tagcloud (Difference)
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Tagcloud (Intersection)
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