U2AF1 and ZCCHC10

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		U2AF1	ZCCHC10
Gene Name		U2 small nuclear RNA auxiliary factor 1	zinc finger, CCHC domain containing 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding RS Domain Binding	Nucleic Acid Binding Zinc Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRPK2 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2	50 interactors: ARGLU1 BEND7 CEP63 CEP70 COIL CTNNBL1 DAB1 DACH1 DHX8 DPPA2 DZIP3 EEF1A1 EPB41 FAM9B FRA10AC1 IK KCTD6 KPNA3 LNX1 LUC7L2 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TCEB3B TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A
Entrez ID		7307	54819
HPRD ID		01871	15699
Ensembl ID		ENSG00000160201	ENSG00000155329
Uniprot IDs		Q01081 Q7Z780	D6R9G7 G3XAM1 Q8TBK6
PDB IDs		1JMT
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus RNA Export From Nucleus MRNA 3'-end Processing Termination Of RNA Polymerase II Transcription RNA 3'-end Processing MRNA Transport Nuclear Export RNA Transport RNA Localization DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Nucleocytoplasmic Transport Nuclear Transport Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Process Regulation Of Gene Expression Cytoplasmic Transport Transcription, DNA-templated RNA Biosynthetic Process Viral Process Transcription From RNA Polymerase II Promoter Intracellular Transport Cellular Macromolecular Complex Assembly Negative Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Cellular Localization Negative Regulation Of RNA Splicing Negative Regulation Of Gene Expression Positive Regulation Of Viral Genome Replication Negative Regulation Of Cellular Metabolic Process	RNA Splicing RNA Processing MRNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Ribonucleoprotein Complex Assembly Transcription, DNA-templated Spliceosomal SnRNP Assembly RNA Biosynthetic Process Cellular Process Cellular Component Assembly Spliceosomal Complex Assembly Ribonucleoprotein Complex Biogenesis Signal Transduction In Response To DNA Damage Cell Cycle Regulation Of Mitotic Cell Cycle Cellular Macromolecular Complex Assembly Regulation Of Cell Cycle Negative Regulation Of Fibroblast Proliferation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Maturation Of 5S RRNA DNA Damage Checkpoint MRNA Splice Site Selection Negative Regulation Of Macromitophagy Positive Regulation Of Cytotoxic T Cell Differentiation Cerebellum Structural Organization Oligodendrocyte Apoptotic Process Viral Penetration Into Host Nucleus
Tagcloud ?		allelic arisen biallelic biallellic chimeric chimerism compromised developmentally es establishes fetal fetuses h19 igf2 igf2r imprinted interstitial mandible manipulation maternal maternally paternally persist persisted polyhydramnios preimplantation repression rs1 totipotency	adcy3 angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg dok2 epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16
Tagcloud (Difference) ?		allelic arisen biallelic biallellic chimeric chimerism compromised developmentally es establishes fetal fetuses h19 igf2 igf2r imprinted interstitial mandible manipulation maternally paternally persist persisted polyhydramnios preimplantation repression rs1 totipotency	adcy3 angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg dok2 epigenomic fdr generational humanmethylation27 illumina infant lends mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16
Tagcloud (Intersection) ?		maternal