U2AF1 and ZRANB2

Number of citations of the paper that reports this interaction (PMID 11448987)
13

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		U2AF1	ZRANB2
Gene Name		U2 small nuclear RNA auxiliary factor 1	zinc finger, RAN-binding domain containing 2
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding RS Domain Binding	Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing	Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRPK2 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2	13 interactors: AKAP17A CSNK2A1 EP300 KIF20A SMN1 SNRNP70 SREK1 SRPK1 SRPK2 SRSF2 TRA2B U2AF1 YY1
Entrez ID		7307	9406
HPRD ID		01871	09185
Ensembl ID		ENSG00000160201	ENSG00000132485
Uniprot IDs		Q01081 Q7Z780	O95218
PDB IDs		1JMT	1N0Z 2K1P 3G9Y
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus RNA Export From Nucleus MRNA 3'-end Processing Termination Of RNA Polymerase II Transcription RNA 3'-end Processing MRNA Transport Nuclear Export RNA Transport RNA Localization DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Nucleocytoplasmic Transport Nuclear Transport Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Process Regulation Of Gene Expression Cytoplasmic Transport Transcription, DNA-templated RNA Biosynthetic Process Viral Process Transcription From RNA Polymerase II Promoter Intracellular Transport Cellular Macromolecular Complex Assembly Negative Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Cellular Localization Negative Regulation Of RNA Splicing Negative Regulation Of Gene Expression Positive Regulation Of Viral Genome Replication Negative Regulation Of Cellular Metabolic Process	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Viral Genome Replication RNA Localization Regulation Of Viral Process Regulation Of RNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Cellular Metabolic Process Spliceosomal Complex Assembly Histone H2B Acetylation Nuclear Speck Organization MRNA Export From Nucleus Regulation Of Viral Genome Replication DNA-templated Transcription, Termination RNA Export From Nucleus Negative Regulation Of Viral Process Metabolic Process MRNA 3'-end Processing Positive Regulation Of Gene Expression Response To Prostaglandin F Regulation Of Gene Expression RNA 3'-end Processing N-terminal Peptidyl-lysine Acetylation Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response RNA Transport Regulation Of Tubulin Deacetylation Ribonucleoprotein Complex Assembly Sperm Chromatin Condensation
Tagcloud ?		allelic arisen biallelic biallellic chimeric chimerism compromised developmentally es establishes fetal fetuses h19 igf2 igf2r imprinted interstitial mandible manipulation maternal maternally paternally persist persisted polyhydramnios preimplantation repression rs1 totipotency	as2 chip clone cne coding cur curcumin curve cytometry differentially enhancement fcm fitted flj36000 g2 graph gucy2gp h2bfxp incrna linc00623 loc100506835 micro nasopharyngeal prism radiosensitivity radiosensitizing sensitization verified worked
Tagcloud (Difference) ?		allelic arisen biallelic biallellic chimeric chimerism compromised developmentally es establishes fetal fetuses h19 igf2 igf2r imprinted interstitial mandible manipulation maternal maternally paternally persist persisted polyhydramnios preimplantation repression rs1 totipotency	as2 chip clone cne coding cur curcumin curve cytometry differentially enhancement fcm fitted flj36000 g2 graph gucy2gp h2bfxp incrna linc00623 loc100506835 micro nasopharyngeal prism radiosensitivity radiosensitizing sensitization verified worked
Tagcloud (Intersection) ?